CAS 910297-57-3

N-(2-Chloro-4-hydroxy-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide

Description:

N-(2-Chloro-4-hydroxy-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, with CAS number 910297-57-3, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as a thiazole, pyrimidine, and piperazine moiety. This compound typically exhibits properties such as moderate solubility in polar solvents, which is influenced by the presence of hydroxyl and amino groups that can engage in hydrogen bonding. Its molecular design suggests potential biological activity, particularly in the context of medicinal chemistry, where it may serve as a lead compound for therapeutic applications. The presence of chlorine and methyl groups may also affect its pharmacokinetic properties, including absorption and distribution. As with many compounds in this class, stability under various conditions, reactivity with other chemical species, and potential toxicity are important characteristics that would need to be evaluated in a laboratory setting.

Formula: C₂₂H₂₆ClN₇O₃S

InChI: InChI=1/C22H26ClN7O3S/c1-13-9-15(32)10-16(23)20(13)28-21(33)17-12-24-22(34-17)27-18-11-19(26-14(2)25-18)30-5-3-29(4-6-30)7-8-31/h9-12,31-32H,3-8H2,1-2H3,(H,28,33)(H,24,25,26,27)

InChI key: InChIKey=YYTXGSVGHHVHNZ-UHFFFAOYSA-N

SMILES: N(C1=CC(N2CCN(CCO)CC2)=NC(C)=N1)C=3SC(C(NC4=C(C)C=C(O)C=C4Cl)=O)=CN3

Synonyms:

• N-(2-Chloro-4-hydroxy-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
• 5-Thiazolecarboxamide, N-(2-chloro-4-hydroxy-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-
• BMS 748730
• 4’-Hydroxy Dasatinib
• N-(2-Chloro-4-hydroxy-6-Methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-Methyl-4
• BMS-748730
• 4'-HYDROXY DASATINIBDISCONTINUED
• BMS748730
• Dasatinib metabolite M20
• N-(2-chloro-4-hydroxy-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

4’-Hydroxy Dasatinib

CAS: 910297-57-3

Formula: C₂₂H₂₆ClN₇O₃S

Molecular weight: 504.01

Ref: 4Z-D-3015

Dasatinib Impurity 12

CAS: 910297-57-3

Formula: C₂₂H₂₆ClN₇O₃S

Molecular weight: 504.01

Ref: ST-EA-CP-D1020

BMS-748730

CAS: 910297-57-3

BMS-748730, also known as 4′-Hydroxy Dasatinib, is a Dasatinib metabolite.

Formula: C₂₂H₂₆ClN₇O₃S

Color and Shape: Solid

Molecular weight: 504.01

Ref: TM-T30540