CAS 910297-58-4

N-[2-chloro-6-(hydroxymethyl)phenyl]-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide

Description:

N-[2-chloro-6-(hydroxymethyl)phenyl]-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide, with CAS number 910297-58-4, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups such as amides, thiazoles, and aromatic rings. This compound exhibits properties typical of pharmaceuticals, including potential bioactivity due to its ability to interact with biological targets. The presence of a piperazine moiety suggests possible applications in medicinal chemistry, particularly in the development of drugs targeting neurological or oncological conditions. Its chlorinated phenyl group and hydroxymethyl substituent may influence its solubility and reactivity, while the thiazole and pyrimidine components could contribute to its pharmacological profile. Overall, this compound's intricate structure and diverse functional groups make it a subject of interest for further research in drug development and therapeutic applications.

Formula: C₂₂H₂₆ClN₇O₃S

InChI: InChI=1/C22H26ClN7O3S/c1-14-25-18(11-19(26-14)30-7-5-29(6-8-30)9-10-31)27-22-24-12-17(34-22)21(33)28-20-15(13-32)3-2-4-16(20)23/h2-4,11-12,31-32H,5-10,13H2,1H3,(H,28,33)(H,24,25,26,27)

SMILES: Cc1nc(cc(n1)N1CCN(CC1)CCO)Nc1ncc(C(=Nc2c(cccc2Cl)CO)O)s1

Hydroxymethyl Dasatinib

CAS: 910297-58-4

Formula: C₂₂H₂₆ClN₇O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 504.01

Ref: 4Z-D-3019

Hydroxymethyl Dasatinib

Controlled Product

CAS: 910297-58-4

Applications An oxidative metabolite of Dasatinib (M24 metabolite); used in the treatment of cancers and immune diseases. It is a COVID19-related research product.
References Jaworski, T., et al.: Xenobiotica, 21, 1451 (1991), Shah, N., et al.: Science, 305, 399 (2004), O'Hare, T., et al.: Cancer Res., 65, 4500 (2005), Das, J., et al.: J. Med. Chem., 49, 6819 (2006), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008),

Formula: C₂₂H₂₆ClN₇O₃S

Color and Shape: Neat

Molecular weight: 504.00

Ref: TR-H946625

Dasatinib Impurity 16

CAS: 910297-58-4

Formula: C₂₂H₂₆ClN₇O₃S

Molecular weight: 504.01

Ref: ST-EA-CP-D1024