CAS 910376-39-5

N-[(1S)-1-(Aminocarbonyl)-2,2-dimethylpropyl]-2,3-dihydro-3-(3-hydroxy-3-methylbutyl)-2-oxo-1H-benzimidazole-1-carboxamide

Description:

N-[(1S)-1-(Aminocarbonyl)-2,2-dimethylpropyl]-2,3-dihydro-3-(3-hydroxy-3-methylbutyl)-2-oxo-1H-benzimidazole-1-carboxamide is a complex organic compound characterized by its benzimidazole core, which is a bicyclic structure containing both benzene and imidazole rings. This compound features multiple functional groups, including an amide and a carbonyl, contributing to its potential biological activity. The presence of a chiral center at the 1-position of the propyl chain suggests that it may exhibit stereoisomerism, which can influence its pharmacological properties. The hydroxy and dimethyl groups enhance its solubility and reactivity, making it suitable for various applications in medicinal chemistry. The compound's structure indicates potential interactions with biological targets, possibly serving as a lead compound in drug development. Its CAS number, 910376-39-5, allows for precise identification in chemical databases, facilitating research and development efforts. Overall, this compound exemplifies the complexity and diversity of modern organic molecules with potential therapeutic applications.

Formula: C₁₉H₂₈N₄O₄

InChI: InChI=1S/C19H28N4O4/c1-18(2,3)14(15(20)24)21-16(25)23-13-9-7-6-8-12(13)22(17(23)26)11-10-19(4,5)27/h6-9,14,27H,10-11H2,1-5H3,(H2,20,24)(H,21,25)/t14-/m1/s1

InChI key: InChIKey=GGNIFXBIJCNXCT-CQSZACIVSA-N

SMILES: C(N[C@@H]([C@](C)(C)C)C(N)=O)(=O)N1C=2C(N(CCC(C)(C)O)C1=O)=CC=CC2

Synonyms:

• 1H-Benzimidazole-1-carboxamide, N-[(1S)-1-(aminocarbonyl)-2,2-dimethylpropyl]-2,3-dihydro-3-(3-hydroxy-3-methylbutyl)-2-oxo-
• N-[(1S)-1-(Aminocarbonyl)-2,2-dimethylpropyl]-2,3-dihydro-3-(3-hydroxy-3-methylbutyl)-2-oxo-1H-benzimidazole-1-carboxamide

PF-03550096

CAS: 910376-39-5

PF-03550096 is an analgesic that inhibits the binding of ligands to CB2 receptors. It has affinity for these receptors, with a Kd of 0.4nM. PF-03550096 also has an inhibitory effect on the release of inflammatory mediators from human visceral muscle cells. PF-03550096 is being developed as a drug for the treatment of pain and inflammation, and may be used to treat hypersensitivity reactions such as asthma, allergic rhinitis, and atopic dermatitis.

Formula: C₁₉H₂₈N₄O₄

Purity: Min. 95%

Molecular weight: 376.4 g/mol

Ref: 3D-KLB37639

PF-03550096

CAS: 910376-39-5

PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1].

Formula: C₁₉H₂₈N₄O₄

Color and Shape: Solid

Molecular weight: 376.45

Ref: TM-T84412