
CAS 91085-70-0
:5-Methoxy-1H-indazole-3-carboxamide
Description:
5-Methoxy-1H-indazole-3-carboxamide is a chemical compound characterized by its indazole core, which is a five-membered aromatic ring containing two nitrogen atoms. The presence of a methoxy group (-OCH3) at the 5-position and a carboxamide group (-C(=O)NH2) at the 3-position contributes to its unique chemical properties. This compound is typically a white to off-white solid and is soluble in organic solvents, which is common for many indazole derivatives. It may exhibit biological activity, making it of interest in pharmaceutical research, particularly in the study of potential therapeutic applications. The molecular structure allows for various interactions, including hydrogen bonding and π-π stacking, which can influence its reactivity and interaction with biological targets. As with many chemical substances, safety data should be consulted before handling, as it may pose risks depending on exposure routes and concentrations. Overall, 5-Methoxy-1H-indazole-3-carboxamide represents a significant compound in the field of medicinal chemistry.
Formula:C9H9N3O2
InChI:InChI=1S/C9H9N3O2/c1-14-5-2-3-7-6(4-5)8(9(10)13)12-11-7/h2-4H,1H3,(H2,10,13)(H,11,12)
InChI key:InChIKey=WPCWPIRGNMZVDK-UHFFFAOYSA-N
SMILES:C(N)(=O)C=1C=2C(NN1)=CC=C(OC)C2
Synonyms:- 5-Methoxy-1H-indazole-3-carboxamide
- 1H-Indazole-3-carboxamide, 5-methoxy-
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Found 1 products.
5-Methoxy-1H-indazole-3-carboxylic acid amide
CAS:Controlled Product<p>5-Methoxy-1H-indazole-3-carboxylic acid amide is a glycogen synthase kinase 3 (GSK3) inhibitor. GSK3 is a serine/threonine protein kinase that regulates glycogen synthase and phosphorylates tau proteins. 5-Methoxy-1H-indazole-3-carboxylic acid amide has been used in the treatment of type 2 diabetes mellitus, Alzheimer's disease and other neurological disorders. The cocrystal structure of 5-methoxy indazole carboxamide with glycogen synthase was determined at 1.2 Å resolution.</p>Formula:C9H9N3O2Purity:Min. 95%Molecular weight:191.19 g/mol
