CAS 911-45-5

Clomiphene

Description:

Clomiphene, with the CAS number 911-45-5, is a non-steroidal fertility medication primarily used to treat ovulatory dysfunction in women, particularly those with polycystic ovary syndrome (PCOS). It functions as a selective estrogen receptor modulator (SERM), meaning it can act as an estrogen antagonist in certain tissues while exhibiting estrogen-like effects in others. Clomiphene is typically administered orally and works by stimulating the hypothalamus to release gonadotropin-releasing hormone (GnRH), which in turn promotes the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland, leading to ovarian stimulation and ovulation. The compound is characterized by its chemical formula C26H28ClNO, and it has a relatively low solubility in water but is soluble in organic solvents. Common side effects may include hot flashes, mood swings, and ovarian hyperstimulation syndrome (OHSS). Clomiphene is generally well-tolerated, making it a widely used option in reproductive medicine.

Formula: C₂₆H₂₈ClNO

InChI: InChI=1/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25-

InChI key: InChIKey=GKIRPKYJQBWNGO-UHFFFAOYSA-N

SMILES: C(=C(Cl)C1=CC=CC=C1)(C2=CC=C(OCCN(CC)CC)C=C2)C3=CC=CC=C3

Synonyms:

• 1-(p-β-Diethylaminoethoxyphenyl)-1,2-diphenyl-2-chloroethylene
• 2 [P-(2''-Chloro-1'', 2''-Diphenylvinyl) Phenoxy] Triethylamine
• 2-(4-(2-Chloro-1,2-diphenylvinyl)phenoxy)-N,N-diethylethanamine
• 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine
• 2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]triethylamine
• 2-[p-(β-Chloro-α-phenylstyryl)phenoxy]triethylamine
• 2-{4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy}-N,N-diethylethanamine
• 213-008-6
• Clomifen
• Clomifeno
• Clomiphene
• Clomiphene B
• Ethanamine, 2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethyl-
• Triethylamine, 2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]-
• 2-[4-(2-Chloro-1,2-diphenylvinyl)phenoxy]-N,N-diethylethan-1-amine
• Clomiphene,E/Z-mixture
• C06917
• CLOMIFENE (CLOMIPHENE)
• (E/Z)-Clomiphene
• Clomifene USP/EP/BP
• E/Z-CloMiphene-d4
• N,N-Diethyl-2-[p-(2-chloro-1,2-diphenylvinyl)phenoxy]ethanamine
• CloMiphene Hydrochloride (E/Z Mixture)

Clomiphene (Mixture of Z and E Isomers)

CAS: 911-45-5

Formula: C₂₆H₂₈ClNO

Color and Shape: Yellow Oil

Molecular weight: 405.97

Ref: 4Z-C-8218

Benzyl Clomiphene Citrate

Controlled Product

CAS: 911-45-5

Formula: C₃₃H₃₄ClNO·C₆H₈O₇

Color and Shape: Neat

Molecular weight: 688.21

Ref: TR-B285788