CAS 911115-16-7

5-[2-[7-(Trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-2-pyridinamine

Description:

5-[2-[7-(Trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-2-pyridinamine is a complex organic compound characterized by its unique structural features, including a pyrazolo-pyrimidine core and multiple trifluoromethyl groups. The presence of these trifluoromethyl groups enhances the compound's lipophilicity and may influence its biological activity. The ethynyl group contributes to the compound's reactivity, potentially allowing for further chemical modifications. This compound is likely to exhibit interesting pharmacological properties, making it a candidate for research in medicinal chemistry, particularly in the development of targeted therapies. Its molecular structure suggests potential interactions with biological targets, which could be explored in drug discovery. Additionally, the compound's solubility and stability in various solvents would be important factors to consider in its application. Overall, this substance represents a class of compounds that may have significant implications in pharmaceutical research and development.

Formula: C₂₁H₁₁F₆N₅

InChI: InChI=1S/C21H11F6N5/c22-20(23,24)15-6-4-13(5-7-15)16-9-17(21(25,26)27)32-19(31-16)14(11-30-32)3-1-12-2-8-18(28)29-10-12/h2,4-11H,(H2,28,29)

InChI key: InChIKey=DMJHZVARRXJSEG-UHFFFAOYSA-N

SMILES: C(#CC=1C=CC(N)=NC1)C2=C3N(C(C(F)(F)F)=CC(=N3)C4=CC=C(C(F)(F)F)C=C4)N=C2

Synonyms:

• RO 4995819
• Decoglurant
• 2-Pyridinamine, 5-[[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-
• 5-[2-[7-(Trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-2-pyridinamine
• 2-Pyridinamine, 5-[2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl]-

Decoglurant

CAS: 911115-16-7

Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.

Formula: C₂₁H₁₁F₆N₅

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 447.34

Ref: TM-T15090

5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

CAS: 911115-16-7

Formula: C₂₁H₁₁F₆N₅

Purity: 95%

Molecular weight: 447.3360

Ref: IN-DA00IGHO

Decoglurant

CAS: 911115-16-7

Decoglurant

Purity: ≥98%

Molecular weight: 447.34g/mol

Ref: 54-BUP08441