CAS 911715-90-7

AZD8797

Description:

AZD8797, with the CAS number 911715-90-7, is a chemical compound that has been investigated primarily for its potential therapeutic applications, particularly in the field of respiratory diseases. It is classified as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4), which plays a crucial role in the regulation of inflammatory processes. By inhibiting PDE4, AZD8797 may help reduce inflammation and improve lung function in conditions such as chronic obstructive pulmonary disease (COPD) and asthma. The compound is characterized by its ability to modulate intracellular signaling pathways, leading to decreased production of pro-inflammatory cytokines. AZD8797 has undergone various stages of clinical trials to assess its efficacy and safety profile. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are essential for determining its therapeutic potential and dosing regimens. As research continues, AZD8797 represents a promising avenue for developing new treatments for inflammatory respiratory conditions.

Synonyms:

• 1-Pentanol, 2-[[2-aMino-5-[[(1S)-1-phenylethyl]thio]thiazolo[4,5-d]pyriMidin-7-yl]aMino]-4-Methyl-, (2R)-
• (R)-2-(2-AMINO-5-((S)-1-PHENYLETHYLTHIO)THIAZOLO[4,5-D]PYRIMIDIN-7-YLAMINO)-4-METHYLPENTAN-1-OL

AZD8797

CAS: 911715-90-7

Formula: C₁₉H₂₅N₅OS₂

Purity: 99%

Molecular weight: 403.5647

Ref: IN-DA01EOL7

AZD8797

CAS: 911715-90-7

AZD8797

Purity: ≥98%

Molecular weight: 403.56g/mol

Ref: 54-BUP04813

AZD 8797

CAS: 911715-90-7

AZD 8797 is a molecule that inhibits the release of neurotrophic factors and induces neuronal death by inhibiting mitochondrial membrane potential. AZD 8797 has also been shown to decrease neuronal function in the brain and to increase microglia activity. It has been shown that AZD 8797 decreases the production of chemokines, which are molecules that attract immune cells such as T-cells and macrophages to the site of infection. This drug has been shown to inhibit HIV infection by decreasing HIV gene expression and increasing the number of CD4+ T cells in mice. AZD 8797 is currently being studied for its effects on Alzheimer's disease, Parkinson's disease, stroke, spinal cord injury, and peripheral nerve injury.

Formula: C₁₉H₂₅N₅OS₂

Purity: Min. 95%

Molecular weight: 403.56 g/mol

Ref: 3D-LLB71590

AZD8797

CAS: 911715-90-7

AZD8797 (KAND567) is a CX3CR1 antagonist with potential protective effects against neuronal damage and prevents nociceptive hypersensitivity in rats.

Formula: C₁₉H₂₅N₅OS₂

Purity: 98.73% - 99.68%

Color and Shape: Solid

Molecular weight: 403.56

Ref: TM-T14384