CAS 911809-23-9

rac-Harzianolide

Controlled Product

CAS: 911809-23-9

Applications rac-Harzianolide is a naturally occurring butenolide (F864050) metabolite found from cultures of Trichoderma harzianum.
References Claydon, N., et al.: Phytochem., 30, 3802 (1991); Vinale, F., et al.: Lett. App. Micriobiol., 48, 705 (2009);

Formula: C₁₃H₁₈O₃

Color and Shape: Neat

Molecular weight: 222.28

Ref: TR-H105300

rac-Harzianolide

CAS: 911809-23-9

rac-Harzianolide is an analog of Harzianolide, a natural product isolated from the fungus Trichoderma sp. It has been shown to have potent anticancer activity by inhibiting kinases involved in cancer cell growth and survival. In human urine, rac-Harzianolide has been detected after oral administration of chitosan-bound rac-Harzianolide. This compound induces apoptosis in cancer cells and inhibits tumor growth in Chinese hamsters. Rac-Harzianolide acts as a kinase inhibitor, blocking the activity of the protein kinases that are essential for cancer cell proliferation and survival. It is considered a promising candidate for the development of novel anticancer agents.

Formula: C₁₃H₁₈O₃

Purity: Min. 95%

Molecular weight: 222.28 g/mol

Ref: 3D-LLB80923