CAS 91188-00-0
:Merafloxacin
Description:
Merafloxacin is a synthetic fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Merafloxacin is characterized by its relatively high potency and favorable pharmacokinetic properties, including good oral bioavailability and tissue penetration. It is typically administered in the form of its hydrochloride salt. The substance is known for its low toxicity profile, although, like other fluoroquinolones, it may be associated with certain side effects, including gastrointestinal disturbances and potential effects on tendons. Merafloxacin's development was aimed at addressing the growing concern of antibiotic resistance, and it has been studied for its efficacy in both human and veterinary medicine. However, its use may be subject to regulatory approval and guidelines depending on the region and specific clinical context.
Formula:C19H23F2N3O3
InChI:InChI=1S/C19H23F2N3O3/c1-3-22-8-11-5-6-24(9-11)17-14(20)7-12-16(15(17)21)23(4-2)10-13(18(12)25)19(26)27/h7,10-11,22H,3-6,8-9H2,1-2H3,(H,26,27)
InChI key:InChIKey=BAYYCLWCHFVRLV-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2F)N3CC(CNCC)CC3
Synonyms:- 1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
- 3-Quinolinecarboxylic acid, 1-ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-
- Merafloxacin
- CI 934
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 4 products.
Merafloxacin
CAS:Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.Formula:C19H23F2N3O3Purity:97.57%Color and Shape:SolidMolecular weight:379.4Merafloxacin
CAS:Formula:C19H23F2N3O3Purity:≥ 98.0%Color and Shape:White to off-white solidMolecular weight:379.4Merafloxacin
CAS:<p>Merafloxacin is a new, potent antibacterial agent that has antiviral activity. Merafloxacin inhibits the synthesis of viral proteins by binding to the ribosomes and preventing the formation of an active ribosomal frameshift. Merafloxacin also prevents virus-induced cell death in coronavirus-infected cells by blocking the release of cytochrome c from mitochondria. Merafloxacin is insoluble in water and is reconstituted with propylene glycol before being used as an intravenous infusion. It does not require dilution prior to administration and can be administered through a peripheral venous line or central venous catheter. The drug is rapidly absorbed after intravenous administration, achieving maximum plasma concentrations within 15 minutes.<br>Merafloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfring</p>Formula:C19H23F2N3O3Purity:Min. 95%Molecular weight:379.4 g/mol
