CAS 912445-05-7

2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-carboxamide, dihydrochloride salt

Description:

2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide, dihydrochloride salt, identified by CAS number 912445-05-7, is a chemical compound characterized by its complex structure, which includes a benzimidazole core and a pyrrolidine moiety. This compound typically exhibits properties such as solubility in water due to the presence of the dihydrochloride salt form, which enhances its ionic character. The presence of the carboxamide functional group contributes to its potential as a bioactive molecule, possibly influencing its interactions with biological targets. The stereochemistry indicated by the (2R) configuration suggests specific spatial arrangements that may affect its pharmacological activity. Compounds of this nature are often investigated for their potential therapeutic applications, particularly in fields such as medicinal chemistry and drug development. Overall, the unique combination of functional groups and structural features makes this compound of interest for further research and application in various scientific domains.

Formula: C₁₃H₁₈Cl₂N₄O

InChI: InChI=1/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1

SMILES: C[C@@]1(CCCN1)c1nc2cccc(c2[nH]1)C(=N)O.Cl.Cl

Synonyms:

• ABT-888.2HCl
• Veliparib 2HCl
• 2-((R)-2-Methylpyrrolidin-2-yl)-1H-benzimidazole-4-carboxamide dihydrochloride
• Veliparib dihydrochloride

ABT-888

CAS: 912445-05-7

Formula: C₁₃H₁₈Cl₂N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.2142

Ref: IN-DA006PFC

Veliparib dihydrochloride

CAS: 912445-05-7

Veliparib dihydrochloride

Purity: ≥95%

Molecular weight: 317.21g/mol

Ref: 54-BUP10821

Veliparib dihydrochloride

CAS: 912445-05-7

Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.

Formula: C₁₃H₁₈Cl₂N₄O

Purity: 98% - 99.81%

Color and Shape: Solid

Molecular weight: 317.21

Ref: TM-T2105