CAS 912671-55-7

2-Hydroxy Estradiol 6-N3-Adenine

Controlled Product

CAS: 912671-55-7

Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.
References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)

Formula: C₂₃H₂₇N₅O₃

Color and Shape: Neat

Molecular weight: 421.49

Ref: TR-H942160