CAS 91300-60-6

6-(Phenylamino)-5,8-quinolinedione

Description:

6-(Phenylamino)-5,8-quinolinedione, identified by its CAS number 91300-60-6, is a synthetic organic compound characterized by its quinoline structure, which features a quinone moiety. This compound typically exhibits a yellow to orange color due to its conjugated system, which can also influence its optical properties. It is known for its potential applications in various fields, including medicinal chemistry and dye synthesis, owing to its ability to interact with biological systems and its stability under certain conditions. The presence of the phenylamino group enhances its reactivity and solubility in organic solvents. Additionally, this compound may exhibit fluorescence, making it useful in analytical applications. Its chemical behavior can be influenced by factors such as pH and solvent polarity, which can affect its ionization state and, consequently, its biological activity. As with many organic compounds, safety precautions should be taken when handling it, as it may pose health risks if ingested or inhaled.

Formula: C₁₅H₁₀N₂O₂

InChI: InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H

InChI key: InChIKey=GXIJYWUWLNHKNW-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=C1NC3=CC=CC=C3)=NC=CC2

Synonyms:

• 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline
• 5,8-Quinolinedione, 6-(phenylamino)-
• 6-(Phenylamino)-5,8-quinolinedione
• 6-Anilinoquinoline-5,8-quinone
• Comr 2029
• Ly 83583
• Ly83583

6-Anilino-5,8-quinolinedione

CAS: 91300-60-6

Formula: C₁₅H₁₀N₂O₂

Purity: 98%

Molecular weight: 250.2521

Ref: IN-DA006OUJ

LY83583

CAS: 91300-60-6

LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.

Formula: C₁₅H₁₀N₂O₂

Purity: 99.54% - 99.80%

Color and Shape: Solid

Molecular weight: 250.25

Ref: TM-T21576

LY83583

CAS: 91300-60-6

LY83583

Purity: ≥98%

Molecular weight: 250.25g/mol

Ref: 54-BUP14279

6-Anilinoquinoline-5,8-quinone

CAS: 91300-60-6

Formula: C₁₅H₁₀N₂O₂

Molecular weight: 250.25

Ref: 7W-GL0827

6-(Phenylamino)quinoline-5,8-dione

CAS: 91300-60-6

6-(Phenylamino)quinoline-5,8-dione

Purity: ≥95%

Color and Shape: Red-Brown Solid

Molecular weight: 250.25g/mol

Ref: 54-OR6450T

6-Anilino-5,8-quinolinedione

Controlled Product

CAS: 91300-60-6

Applications Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2µM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
References Macleod, K.M., et al.: Mol. Pharmacol., 32, 59 (1987), Mulsch, A. J.: J. Pharmacol. Exp. Ther., 247, 283 (1988), Mulsch, A., et al.: Naunyn-Schmiedeberg's Arch. Pharmacol., 340, 119 (1989), Light, D.B., et al.: Science, 243, 383 (1989), Beasley, D., et al.: J. Clin. Invest., 87, 602 (1991)

Formula: C₁₅H₁₀N₂O₂

Color and Shape: Neat

Molecular weight: 250.25

Ref: TR-A664500

6-Anilinoquinoline-5,8-quinone

CAS: 91300-60-6

6-Anilinoquinoline-5,8-quinone is a chemical compound that belongs to the family of cyclase inhibitors. It has been shown to inhibit cyclase and cytosolic Ca2+, which are intracellular targets for HIV infection. 6-Anilinoquinoline-5,8-quinone inhibits the transcription of HIV by binding to dinucleotide phosphate in the cell nucleus. This compound has also been shown to have anti-inflammatory properties through its ability to inhibit prostaglandin synthesis and reduce the production of inflammatory cytokines. 6-Anilinoquinoline-5,8-quinone has been shown to be pluripotent in vitro and can induce a number of physiological effects in cells such as increased protein synthesis and reduced cellular respiration.

Formula: C₁₅H₁₀N₂O₂

Purity: Min. 95%

Molecular weight: 250.25 g/mol

Ref: 3D-RDA30060