CAS 913376-84-8

N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide

Description:

N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide is a complex organic compound characterized by its diverse functional groups and structural features. It contains a pyrazole core, which is known for its biological activity, particularly in medicinal chemistry. The presence of a fluorine atom and a methoxyquinoline moiety suggests potential interactions with biological targets, enhancing its pharmacological profile. The compound also features a carboxamide group, which can influence solubility and binding properties. Its structure indicates potential applications in drug development, particularly in areas targeting specific receptors or enzymes. The presence of multiple aromatic rings may contribute to its stability and lipophilicity, affecting its bioavailability. Overall, this compound exemplifies the complexity often found in pharmaceutical agents, combining various chemical functionalities that may lead to unique therapeutic effects. Further studies would be necessary to elucidate its specific biological activities and potential applications.

Formula: C₃₁H₂₉FN₄O₅

InChI: InChI=1S/C31H29FN4O5/c1-19-28(30(38)36(21-8-6-5-7-9-21)35(19)18-31(2,3)39)29(37)34-20-10-13-27(24(32)16-20)41-26-14-15-33-25-17-22(40-4)11-12-23(25)26/h5-17,39H,18H2,1-4H3,(H,34,37)

InChI key: InChIKey=UYMSIPINLJNNOU-UHFFFAOYSA-N

SMILES: C(C(C)(C)O)N1N(C(=O)C(C(NC2=CC(F)=C(OC=3C4=C(C=C(OC)C=C4)N=CC3)C=C2)=O)=C1C)C5=CC=CC=C5

Synonyms:

• 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl]-2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-
• SYN 1143
• Kin237
• N-[3-Fluoro-4-[(7-methoxyquinolin-4-yl)oxy]phenyl]-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
• N-[3-Fluoro-4-[(7-methoxy-4-quinolinyl)oxy]phenyl]-2,3-dihydro-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide
• AMG-1
• AMG1;AMG 1

AMG-1

CAS: 913376-84-8

Formula: C₃₁H₂₉FN₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 556.5842

Ref: IN-DA00H14F

N-(3-Fluoro-4-((7-Methoxyquinolin-4-Yl)Oxy)Phenyl)-1-(2-Hydroxy-2-Methylpropyl)-5-Methyl-3-Oxo-2-Phenyl-2,3-Dihydro-1H-Pyrazole-4-Carboxamide

CAS: 913376-84-8

N-(3-Fluoro-4-((7-Methoxyquinolin-4-Yl)Oxy)Phenyl)-1-(2-Hydroxy-2-Methylpropyl)-5-Methyl-3-Oxo-2-Phenyl-2,3-Dihydro-1H-Pyrazole-4-Carboxamide

Purity: 98%

Molecular weight: 556.58g/mol

Ref: 54-PC108405

SYN1143

CAS: 913376-84-8

SYN1143

Purity: ≥98%

Molecular weight: 556.58g/mol

Ref: 54-BUP09683

SYN1143

CAS: 913376-84-8

SYN1143 (AMG-1) strongly inhibits RON & c-Met with IC50s: 9 & 4 nmol/L.

Formula: C₃₁H₂₉FN₄O₅

Purity: 99.69%

Color and Shape: Solid

Molecular weight: 556.58

Ref: TM-T8409

AMG-1

CAS: 913376-84-8

Ref: 7W-GW1838