DOTA di(tBu)ester, known chemically as 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid di(t-butyl) ester, is a derivative of the DOTA ligand, which is widely used in coordination chemistry and radiopharmaceutical applications. This compound features a macrocyclic structure with four nitrogen atoms and four carboxylic acid groups, which are esterified with t-butyl groups, enhancing its lipophilicity and stability. DOTA di(tBu)ester is characterized by its ability to form stable complexes with various metal ions, particularly lanthanides and transition metals, making it valuable in the development of imaging agents and targeted therapies in nuclear medicine. The presence of t-butyl esters also contributes to its solubility in organic solvents, facilitating its use in various chemical reactions and formulations. Additionally, the compound's stability and reactivity can be influenced by the choice of metal ion, which can affect its application in radiolabeling and drug delivery systems. Overall, DOTA di(tBu)ester is a versatile compound with significant implications in both research and clinical settings.

DOTA di(tBu)ester

913542-71-9: DOTA di(tBu)ester, known chemically as 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid di(t-butyl) ester, is a derivative of the DOTA ligand, which is widely used in coordination chemistry and radiopharmaceutical applications. This compound features a macrocyclic structure with four nitrogen atoms and four carboxylic acid groups, which are esterified with t-butyl groups, enhancing its lipophilicity and stability. DOTA di(tBu)ester is characterized by its ability to form stable complexes with various metal ions, particularly lanthanides and transition metals, making it valuable in the development of imaging agents and targeted therapies in nuclear medicine. The presence of t-butyl esters also contributes to its solubility in organic solvents, facilitating its use in various chemical reactions and formulations. Additionally, the compound's stability and reactivity can be influenced by the choice of metal ion, which can affect its application in radiolabeling and drug delivery systems. Overall, DOTA di(tBu)ester is a versatile compound with significant implications in both research and clinical settings.

2,2'-(4,10-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetic acid

CAS 913542-71-9

DOTA di(tBu)ester

2,2'-(4,10-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,7-diyl)diacetic acid

Ref: 54-OR1072871