CAS 913611-97-9

Brexpiprazole

Description:

Brexpiprazole is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and as an adjunctive therapy for major depressive disorder. It acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, while also functioning as an antagonist at serotonin 5-HT2A receptors, which contributes to its therapeutic effects. The chemical formula of brexpiprazole is C24H27N3O2, and it features a piperazine ring, which is common in many psychotropic medications. Brexpiprazole is characterized by its relatively long half-life, allowing for once-daily dosing, which can enhance patient compliance. The substance is typically administered orally and is well-absorbed, with peak plasma concentrations occurring within a few hours post-ingestion. Side effects may include weight gain, sedation, and metabolic changes, similar to other medications in its class. Overall, brexpiprazole represents a significant advancement in the pharmacological management of certain psychiatric disorders, offering a favorable side effect profile compared to older antipsychotics.

Formula: C₂₅H₂₇N₃O₂S

InChI: InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29)

InChI key: InChIKey=ZKIAIYBUSXZPLP-UHFFFAOYSA-N

SMILES: C(CCCOC=1C=C2C(=CC1)C=CC(=O)N2)N3CCN(C4=C5C(SC=C5)=CC=C4)CC3

Synonyms:

• 2(1H)-Quinolinone, 7-[4-(4-benzo[b]thien-4-yl-1-piperazinyl)butoxy]-
• 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one
• 7-[4-(4-Benzo[b]thien-4-yl-1-piperazinyl)butoxy]-2(1H)-quinolinone
• Opc 34712
• Rexulti
• Rxulti
• Brexpiprazole

Brexpiprazole

CAS: 913611-97-9

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₅H₂₇N₃O₂S

Color and Shape: White Pale Yellow Crystalline Powder

Molecular weight: 433.1824

Ref: 45-1076356

Brexpiprazole

CAS: 913611-97-9

Formula: C₂₅H₂₇N₃O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 433.5658

Ref: IN-DA00GRAY

Brexpiprazole

CAS: 913611-97-9

Brexpiprazole

Purity: ≥98%

Molecular weight: 433.57g/mol

Ref: 54-BUP15463

Brexpiprazole

CAS: 913611-97-9

Formula: C₂₅H₂₇N₃O₂S

Color and Shape: White To Off-White Solid

Molecular weight: 433.57

Ref: 4Z-B-115001

Brexpiprazole

Controlled Product

CAS: 913611-97-9

Formula: C₂₅H₂₇N₃O₂S

Color and Shape: Neat

Molecular weight: 433.57

Ref: 86-MM3702.00

Brexpiprazole

CAS: 913611-97-9

Brexpiprazole (OPC-34712) is a partial agonist of human 5-hydroxytryptamine (5-HT) 5-HT1A and dopamine D2 receptors.

Formula: C₂₅H₂₇N₃O₂S

Purity: 99.06% - 99.96%

Color and Shape: Solid

Molecular weight: 433.57

Ref: TM-T2306

Brexpiprazole

Controlled Product

CAS: 913611-97-9

Applications Brexpiprazole is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders.
References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006);

Formula: C₂₅H₂₇N₃O₂S

Color and Shape: White To Light Brown

Molecular weight: 433.57

Ref: TR-B677385

Brexpiprazole

Controlled Product

CAS: 913611-97-9

Brexpiprazole is a dopamine D2 receptor partial agonist with adjunctive antipsychotic activity for the treatment of schizophrenia. Brexpiprazole has been shown to have minimal effects on the concentration–time curve or pharmacokinetics of other antipsychotics, and it does not cause extrapyramidal symptoms. Brexpiprazole has also been shown to be effective in the treatment of major depressive disorder.

Formula: C₂₅H₂₇N₃O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 433.57 g/mol

Ref: 3D-FB106463