CAS 91366-65-3

7-Fluorobenzofurazan-4-sulfonamide

Description:

7-Fluorobenzofurazan-4-sulfonamide is a chemical compound characterized by its unique structure, which includes a benzofurazan moiety substituted with a fluorine atom and a sulfonamide group. This compound typically exhibits a high degree of stability due to the presence of the sulfonamide functional group, which enhances its solubility in polar solvents. The fluorine substitution can influence its electronic properties, potentially enhancing its reactivity and biological activity. As a sulfonamide, it may exhibit antimicrobial properties, making it of interest in pharmaceutical applications. The compound's molecular structure contributes to its potential utility in various chemical reactions, including those involving nucleophilic substitutions. Additionally, its unique characteristics may allow for specific interactions with biological targets, which can be explored in drug development. Overall, 7-Fluorobenzofurazan-4-sulfonamide represents a versatile compound with potential applications in medicinal chemistry and materials science.

Formula: C₆H₄FN₃O₃S

InChI: InChI=1/C6H4FN3O3S/c7-3-1-2-4(14(8,11)12)6-5(3)9-13-10-6/h1-2H,(H2,8,11,12)

SMILES: c1cc(c2c(c1F)non2)S(=O)(=O)N

Synonyms:

• 7-Fluoro-2,1,3-Benzoxadiazole-4-Sulfonamide
• 4-Fluoro-7-sulfamoylbenzofurazan
• 7-Fluorobenzo[c][1,2,5]oxadiazole-4-sulfonamide
• 4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole

ABD-F [=4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for Determination of Thiols]

CAS: 91366-65-3

Formula: C₆H₄FN₃O₃S

Purity: >98.0%(T)(N)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 217.17

Ref: 3B-A5597

7-Fluorobenzofurazan-4-sulfonamide, 98%

CAS: 91366-65-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₄FN₃O₃S

Purity: 98%

Color and Shape: Pale yellow, Powder

Molecular weight: 217.17

Ref: 02-B23586

7-Fluorobenzo[c][1,2,5]oxadiazole-4-sulfonamide

CAS: 91366-65-3

Formula: C₆H₄FN₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 217.1777

Ref: IN-DA003NLX

ABD-F

CAS: 91366-65-3

ABD-F is a highly reactive fluorescent reagent for thiol groups in thiol-containing amino acids, proteins, and tissues.

Formula: C₆H₄FN₃O₃S

Purity: 99.64%

Color and Shape: Solid

Molecular weight: 217.18

Ref: TM-T83860

4-(Aminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole

CAS: 91366-65-3

4-(Aminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole

Formula: C₆H₄FN₃O₃S

Purity: 98%

Color and Shape: colourless to pale yellow solid

Molecular weight: 217.18g/mol

Ref: 54-PC8114

ABD-F

CAS: 91366-65-3

Formula: C₆H₄FN₃O₃S

Molecular weight: 217.17

Ref: 7W-GT6137

4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole

CAS: 91366-65-3

Applications A water soluble pH dependent bifunctional fluorogenic reagent for the sensitive and specific detection of protein thiols. ABD-F is highly reactive and specific for protein thiols, and its selectivity is superior to that of other sulfhydryl-reactive fluorophores such as fluorescein maleimide, 5-iodoacetamidofluorescein, 5-I-AEDANS, dansylaziridine, and bimane. Fluorescence: max Abs. l = 385nm, max Em. l = 520nm; Molar Abs. > 4.5x103 (ca. 315nm)
References Hiratsuka., T.,: J. Biol. Chem., 268, 24742 (1993), Treuheit, M.J., et al.: Anal. Biochem., 212, 138 (1993), Takeda., S., et al.: Trans. Mater. Res. Soc. Jpn., 15A, 509 (1994), Tukushima, T., et al.: Biomed. Chromatogr., 9, 10 (1995), Takeda., S., et al.: J. Biochem., 117, 267 (1995)

Formula: C₆H₄FN₃O₃S

Color and Shape: Neat

Molecular weight: 217.18

Ref: TR-A629400

4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole

CAS: 91366-65-3

4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (AFB) is a reagent that has been used to detect the presence of galacturonic acid in cell culture. It is also a potent inhibitor of enzymes such as catalase and peroxidase. AFB binds to the sulfhydryl groups on enzymes, thereby preventing them from performing their catalytic function. The reducing power of AFB can be used as an indicator of the redox potentials in a sample. When AFB reacts with trifluoroacetic acid, it forms a disulfide bond and changes its color from yellow to blue. This change can be detected by UV spectroscopy or other analytical methods.

Formula: C₆H₄FN₃O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 217.18 g/mol

Ref: 3D-FA17851

4-(Aminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole

CAS: 91366-65-3

Formula: C₆H₄FN₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 217.17

Ref: 10-F009442