CAS 913830-15-6

3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzonitrile

CAS: 913830-15-6

Formula: C₁₄H₈N₄O

Purity: 99%

Molecular weight: 248.2395

Ref: IN-DA00H1JO

NS9283

CAS: 913830-15-6

NS9283

Purity: ≥98%

Molecular weight: 248.24g/mol

Ref: 54-BUP07364

NS9283

CAS: 913830-15-6

NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.

Formula: C₁₄H₈N₄O

Purity: 99.12%

Color and Shape: Solid

Molecular weight: 248.24

Ref: TM-T28199

NS 9283

Controlled Product

CAS: 913830-15-6

Applications NS 9283 is a positive allosteric modulator of α4β2 receptor affecting the potency of acetylcholine (Ach) related events. This has been linked to affect on everyday brain function including cognitive function and pain alleviation.
References Olsen, J. et al.: J. Biol. Chem., 288, 35997 (2013); Marotta, C. et al.: ACS Chem. Biol., 9, 1153 (2014);

Formula: C₁₄H₈N₄O

Color and Shape: Neat

Molecular weight: 248.24

Ref: TR-N900260

NS 9283

CAS: 913830-15-6

NS-9283 is a monoclonal antibody that targets the human protein called SPARC. NS-9283 is being developed as a diagnostic and prognostic marker for squamous cell carcinoma of the lung, which is currently diagnosed by a chemiluminescence method. It has been shown to be a potential biomarker for cardiac muscle and diabetic neuropathy. NS-9283 binds to SPARC and inhibits its function, leading to cell death. The antibody has also been shown to bind with high affinity to the surface of cancer cells in culture, which may be due to its ability to cross the blood-brain barrier. This binding leads to the activation of complement and cell lysis.

Formula: C₁₄H₈N₄O

Purity: Min. 95%

Molecular weight: 248.24 g/mol

Ref: 3D-NLB83015