CAS 913844-45-8

H-1152 Glycyl Dihydrochloride

Controlled Product

CAS: 913844-45-8

Stability Hygroscopic
Applications A glycyl analog of Rho-kinase (ROCK) inhibitor that inhibits ROCK with an improved selectitity; for treatment of hypertension and arteriosclerosis.
References Tamura, M., et al.: Biochim. Biophys. Acta, 1754, 245 (2005),

Formula: C₁₈H₂₄N₄O₃S·2ClH

Color and Shape: Neat

Molecular weight: 449.4

Ref: TR-H011530

Glycyl-H 1152 dihydrochloride

CAS: 913844-45-8

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Formula: C₁₈H₂₄N₄O₃S•(HCl)₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 449.4 g/mol

Ref: 3D-FG23695

Glycyl H-1152 hydrochloride

CAS: 913844-45-8

Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.

Formula: C₁₈H₂₆Cl₂N₄O₃S

Color and Shape: Solid

Molecular weight: 449.39

Ref: TM-T35459