CAS 914462-92-3: 1,7-Diazaspiro[4.5]decan-2-one, 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-, hydrochloride, hydrate (1:1:1), (5S,8S)-

Formula: C₂₅H₂₆F₆N₂O₂·ClH·H₂O

InChI: InChI=1S/C25H26F6N2O2.ClH.H2O/c1-16(17-11-19(24(26,27)28)13-20(12-17)25(29,30)31)35-15-23(18-5-3-2-4-6-18)10-9-22(14-32-23)8-7-21(34)33-22;;/h2-6,11-13,16,32H,7-10,14-15H2,1H3,(H,33,34);1H;1H2/t16-,22-,23-;;/m1../s1

InChI key: InChIKey=GZQWMYVDLCUBQX-WVZIYJGPSA-N

SMILES: Cl.O=C1NC2(CNC(C=3C=CC=CC3)(COC(C=4C=C(C=C(C4)C(F)(F)F)C(F)(F)F)C)CC2)CC1.O

Synonyms:

• 1,7-Diazaspiro[4.5]decan-2-one, 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-, monohydrochloride, monohydrate, (5S,8S)-
• Sch 619734 monohydrate
• Rolapitant hydrochloride hydrate
• Rolapitant hydrochloride monohydrate
• 1,7-Diazaspiro[4.5]decan-2-one, 8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-, hydrochloride, hydrate (1:1:1), (5S,8S)-

Rolapitant hydrochloride monohydrate

CAS: 914462-92-3

• Formula: C₂₅H₂₇ClF₆N₂O₂
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 536.9375

Rolapitant hydrochloride hydrate

CAS: 914462-92-3

Rolapitant (SCH-619734) is a selective NK1-receptor antagonist that may prevent nausea and vomiting induced by …

• Formula: C₂₅H₂₉ClF₆N₂O₃
• Color and Shape: Liquid
• Molecular weight: 554.95

Rolapitant hydrochloride monohydrate

CAS: 914462-92-3

Neurokinin-1 (NK-1) receptor antagonist

• Formula: C₂₅H₂₇ClF₆N₂O₂·H₂O
• Purity: Min. 95%
• Color and Shape: White To Off-White Solid
• Molecular weight: 554.95 g/mol