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CAS 91488-21-0

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Demethyl Naproxen Acyl-β-D-glucuronide

Description:
Demethyl Naproxen Acyl-β-D-glucuronide is a chemical compound that serves as a metabolite of the nonsteroidal anti-inflammatory drug (NSAID) naproxen. It is characterized by the presence of a glucuronic acid moiety, which is a common feature in drug metabolism, facilitating the excretion of lipophilic compounds by converting them into more hydrophilic forms. This compound is typically formed through the conjugation of naproxen with glucuronic acid, a process that enhances its solubility in water and promotes renal elimination. The structure of Demethyl Naproxen Acyl-β-D-glucuronide includes a demethylated naproxen core, which contributes to its pharmacological properties. As a metabolite, it may exhibit reduced anti-inflammatory activity compared to its parent compound, but it can still play a role in the overall pharmacokinetics and pharmacodynamics of naproxen. Understanding such metabolites is crucial for assessing the safety and efficacy of NSAIDs in clinical settings.
Formula:C19H20O9
Synonyms:
  • Demethyl Naproxen Acyl-β-D-glucuronide
  • 1-(6-Methoxy-2-naphthaleneacetate)
  • β-D-Glucopyranuronic acid, 1-(6-methoxy-2-naphthaleneacetate)
  • Afobazole Impurity 9
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