CAS 914927-40-5

3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile

Description:

3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile is a chemical compound characterized by its indole core, which is a bicyclic structure consisting of a benzene ring fused to a pyrrole ring. The presence of a hydroxyl group (-OH) at the 4-position of the butyl chain contributes to its hydrophilicity, while the carbonitrile group (-C≡N) at the 5-position of the indole enhances its reactivity and potential for forming various derivatives. This compound may exhibit biological activity, making it of interest in medicinal chemistry and drug development. Its molecular structure suggests potential interactions with biological targets, possibly influencing pathways related to neurotransmission or other physiological processes. Additionally, the compound's solubility, stability, and reactivity can be influenced by the functional groups present, which may affect its application in research or industry. As with many indole derivatives, it may also possess fluorescent properties, making it useful in various analytical techniques.

3-(4-Hydroxybutyl)-1H-Indole-5-Carbonitrile

CAS: 914927-40-5

Formula: C₁₃H₁₄N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 214.2631

Ref: IN-DA00GTXX

3-(4-Hydroxybutyl)-1H-Indole-5-carbonitrile

CAS: 914927-40-5

3-(4-Hydroxybutyl)-1H-Indole-5-carbonitrile

Purity: 95%

Molecular weight: 214.26g/mol

Ref: 54-OR87049

Vilazodone Impurity 7

CAS: 914927-40-5

Formula: C₁₃H₁₄N₂O

Molecular weight: 214.27

Ref: 4Z-V-2114

3-(4-Hydroxybutyl)-1H-Indole-5-carbonitrile

Controlled Product

CAS: 914927-40-5

Applications 3-(4-Hydroxybutyl)-1H-Indole-5-carbonitrile is an impurity of Vilazodone (V265000), a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.
References Bartoszyk, G., et al.: Eur. J. Pharmacol., 322, 147 (1997); Heinrich, T., et al.: J. Med. Chem., 47, 4684 (2004)

Formula: C₁₃H₁₄N₂O

Color and Shape: Neat

Molecular weight: 214.26

Ref: TR-H830830

3-(4-Hydroxybutyl)-1H-Indole-5-carbonitrile

CAS: 914927-40-5

3-(4-Hydroxybutyl)-1H-Indole-5-carbonitrile is an intermediate in the synthesis of vilazodone, a drug that is used to treat depression. It can be synthesized from 3-(4-hydroxyphenyl)acetonitrile and 2,3-dichloroaniline.

Formula: C₁₃H₁₄N₂O

Purity: Min. 95%

Molecular weight: 214.26 g/mol

Ref: 3D-PLB92740

Vilazodone Impurity 7

CAS: 914927-40-5

Formula: C₁₃H₁₄N₂O

Molecular weight: 214.27

Ref: ST-EA-CP-V18001