CAS 914937-68-1

5-Pyrimidinecarboxamide, 2-[6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-

Description:

5-Pyrimidinecarboxamide, 2-[6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy- is a complex organic compound characterized by its unique structural features, including a pyrimidine ring and a quinoline moiety. The presence of a hydroxylamine functional group contributes to its potential reactivity and biological activity. This compound is likely to exhibit properties typical of amides, such as moderate solubility in polar solvents and potential hydrogen bonding capabilities. The fluorine atom in the quinoline structure may enhance lipophilicity and influence the compound's pharmacokinetic properties. Additionally, the bicyclic structure may impart rigidity, affecting its conformational flexibility and interactions with biological targets. Given its intricate structure, this compound may be of interest in medicinal chemistry, particularly in the development of pharmaceuticals targeting specific biological pathways. However, detailed studies would be necessary to fully elucidate its properties, including its stability, reactivity, and biological activity.

Formula: C₂₀H₁₉FN₆O₂

Synonyms:

• 5-Pyrimidinecarboxamide, 2-[6-[[(6-fluoro-2-quinolinyl)methyl]amino]-3-azabicyclo[3.1.0]hex-3-yl]-N-hydroxy-

(Rac)-Nanatinostat

CAS: 914937-68-1

(Rac)-Nanatinostat ((Rac)-CHR-3996, example 44) is a potent HDAC inhibitor with an IC50 of less than 330 nM. It exhibits anticancer properties, effectively inhibiting the growth of HeLa, U937, and HUT cells.

Formula: C₂₀H₁₉FN₆O₂

Color and Shape: Solid

Molecular weight: 394.402

Ref: TM-T205112