CAS 915082-52-9

A 33

CAS: 915082-52-9

Formula: C₁₉H₁₈ClN₃O₂S

Purity: 99%

Molecular weight: 387.8831

Ref: IN-DA01LMHW

PDE4B-IN-2

CAS: 915082-52-9

PDE4B-IN-2

Purity: ≥98%

Molecular weight: 387.88g/mol

Ref: 54-BUP07427

A 33

CAS: 915082-52-9

A 33 is a polymeric matrix that is programmable and can be used to create an osmotic device. It consists of a fibre with a cyclic oligomeric matrix (COM) that is hydrophilic on one side and hydrophobic on the other. The two surfaces are connected by a membrane. The COM is designed to change the pH of the solution on either side, depending on the desired effect. For example, if it is desirable for the system to maintain a basic pH, then the hydrophobic side should be placed in contact with an acidic solution, while the hydrophilic side should be placed in contact with a basic solution. This produces an osmotic system that has different properties at different pH levels. A 33 has been tested as a treatment for systemic sclerosis and has shown promising results in animal models.

Formula: C₁₉H₁₈ClN₃O₂S

Purity: Min. 95%

Molecular weight: 387.9 g/mol

Ref: 3D-QLB08252

PDE4B-IN-2

CAS: 915082-52-9

PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.

Formula: C₁₉H₁₈ClN₃O₂S

Purity: 99.32%

Color and Shape: Solid

Molecular weight: 387.88

Ref: TM-T36832