CAS 91524-15-1

Irloxacin

Description:

Irloxacin is a synthetic fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity. It is primarily used in the treatment of various bacterial infections, particularly those caused by Gram-negative and some Gram-positive organisms. The compound functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription, thereby preventing bacterial cell division and growth. Irloxacin is characterized by its relatively high solubility in water and organic solvents, which facilitates its absorption and distribution in biological systems. The substance typically presents as a white to off-white crystalline powder. Its pharmacokinetic properties include good oral bioavailability, with a half-life that allows for convenient dosing regimens. However, like other fluoroquinolones, Irloxacin may be associated with potential side effects, including gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. As with any antibiotic, it is essential to use Irloxacin judiciously to minimize the risk of developing antibiotic resistance.

Formula: C₁₆H₁₃FN₂O₃

InChI: InChI=1S/C16H13FN2O3/c1-2-18-9-11(16(21)22)15(20)10-7-12(17)14(8-13(10)18)19-5-3-4-6-19/h3-9H,2H2,1H3,(H,21,22)

InChI key: InChIKey=RZLHGQLYNZQZQQ-UHFFFAOYSA-N

SMILES: C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3C=CC=C3

Synonyms:

• Irloxacino [Spanish]
• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-
• 3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1H-pyrrol-1-yl)-
• E 3432
• Irloxacin [INN]
• Pirfloxacin
• Irloxacine [French]
• UNII-36SG77D21B
• 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1H-pyrrol-1-yl)-3-quinolinecarboxylic acid
• Pirfloxacin
• E 3432
• Irloxacinum
• 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-3-quinolinecarboxylic acid
• Irloxacinum [Latin]
• Irloxacino
• 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-pyrrol-1-yl-3-quinolinecarboxylic acid
• Irloxacine
• NSC 610496
• Irloxacin
• 1-ethyl-6-fluoro-4-oxo-7-(1H-pyrrol-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-

Irloxacin

CAS: 91524-15-1

Irloxacin

Purity: ≥98%

Molecular weight: 300.28g/mol

Ref: 54-BUP07636

Irloxacin

CAS: 91524-15-1

Irloxacin, a new quinolone, works best in acid pH, effectively targeting both gram-positive and negative bacteria.

Formula: C₁₆H₁₃FN₂O₃

Purity: 99.71%

Color and Shape: Solid

Molecular weight: 300.28

Ref: TM-T9680