CAS 91590-75-9

Momordicin II

Description:

Momordicin II is a triterpenoid compound primarily extracted from the fruit of the bitter melon plant, scientifically known as Momordica charantia. This compound is notable for its potential medicinal properties, particularly in traditional medicine systems. Momordicin II exhibits a range of biological activities, including anti-diabetic, anti-inflammatory, and anti-cancer effects, making it a subject of interest in pharmacological research. Its structure features a complex arrangement of carbon rings typical of triterpenoids, contributing to its biological activity. Additionally, Momordicin II is known for its bitter taste, which is characteristic of many compounds derived from bitter melon. The compound's mechanism of action is believed to involve modulation of glucose metabolism and insulin sensitivity, which is particularly relevant for diabetes management. While research continues to explore its full therapeutic potential, safety and efficacy in clinical applications remain areas of ongoing investigation. Overall, Momordicin II represents a significant natural product with promising health benefits, warranting further study in the context of modern medicine.

Formula: C₃₆H₅₈O₉

InChI: InChI=1S/C36H58O9/c1-19(2)14-21(44-32-30(43)29(42)28(41)26(17-37)45-32)15-20(3)22-10-11-35(7)31-25(39)16-24-23(8-9-27(40)33(24,4)5)36(31,18-38)13-12-34(22,35)6/h14,16,18,20-23,25-32,37,39-43H,8-13,15,17H2,1-7H3/t20-,21?,22-,23-,25+,26-,27+,28-,29+,30-,31+,32-,34-,35+,36-/m1/s1

InChI key: InChIKey=WCYLDCDQWJYEPO-RMDIKJGVSA-N

SMILES: C(=O)[C@]12[C@]([C@@]3(C)[C@](C)(CC1)[C@@]([C@@H](CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C(C)C)C)(CC3)[H])([C@@H](O)C=C5[C@]2(CC[C@H](O)C5(C)C)[H])[H]

Synonyms:

• 19-Norlanosta-5,24-diene-9-carboxaldehyde, 23-(β-D-glucopyranosyloxy)-3,7-dihydroxy-, (3β,7β,9β,10α)-
• Momordicine II
• (3β,7β,9β,10α)-23-(β-D-Glucopyranosyloxy)-3,7-dihydroxy-19-norlanosta-5,24-diene-9-carboxaldehyde
• Momordicin II
• Momordicine I 23-β-D-glucopyranoside

Momordicine II

CAS: 91590-75-9

Momordicine II may have antidiabetic activity, it significantly stimulated insulin secretion. It also can deter oviposition by L. trifolii significantly.

Formula: C₃₆H₅₈O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 634.851

Ref: TM-TN4576

Momordicine II

CAS: 91590-75-9

Momordicine II is a bioactive compound, which is a triterpenoid saponin derived from the plant Momordica charantia, commonly known as bitter melon. It is extracted primarily from the fruit and seeds of this plant. The mode of action for Momordicine II involves its interaction with various cellular pathways, including those related to glucose metabolism and cancer cell apoptosis. This compound exhibits hypoglycemic effects by modulating insulin pathways and enhancing glucose uptake in cells. Additionally, it induces apoptosis in certain cancer cells by influencing mitochondrial pathways and disrupting cellular homeostasis.

Formula: C₃₆H₅₈O₉

Purity: Min. 95%

Molecular weight: 634.8 g/mol

Ref: 3D-RDA59075