CAS: 916072-89-4 - (5α)-17-(Cyclopropylmethyl)-6,7-didehydro-4,5-epoxy-3,6,14-trihydroxy-N-[1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]morphinan-7-carboxamide

Formula: C₃₂H₃₄N₄O₆

InChI: InChI=1S/C32H34N4O6/c1-30(2,29-33-27(35-42-29)18-6-4-3-5-7-18)34-28(39)20-15-32(40)22-14-19-10-11-21(37)25-23(19)31(32,26(41-25)24(20)38)12-13-36(22)16-17-8-9-17/h3-7,10-11,17,22,26,37-38,40H,8-9,12-16H2,1-2H3,(H,34,39)/t22-,26+,31+,32-/m1/s1

InChI key: InChIKey=AXQACEQYCPKDMV-RZAWKFBISA-N

SMILES: O=C(NC(C1=NC(=NO1)C=2C=CC=CC2)(C)C)C3=C(O)C4OC=5C(O)=CC=C6C5C74CCN(CC8CC8)C(C6)C7(O)C3

Synonyms:

• Naldemedine
• (5α)-17-(Cyclopropylmethyl)-6,7-didehydro-4,5-epoxy-3,6,14-trihydroxy-N-[1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]morphinan-7-carboxamide
• Nalmedine
• Symproic
• Morphinan-7-carboxamide, 17-(cyclopropylmethyl)-6,7-didehydro-4,5-epoxy-3,6,14-trihydroxy-N-[1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]-, (5α)-

Naldemedine-d3

CAS: 916072-89-4

• Formula: C₃₂D₃H₃₁N₄O₆
• Color and Shape: Neat
• Molecular weight: 573.654

Naldemedine

CAS: 916072-89-4

Applications Naldemedine is a peripherally selective mu opioid receptor antagonist used in the treatment in …

• Formula: C₃₂H₃₄N₄O₆
• Color and Shape: Neat
• Molecular weight: 570.64

Naldemedine-d3

CAS: 916072-89-4

Naldemedine is an opioid receptor antagonist that blocks the binding of opioids to their receptors …

• Formula: C₃₂H₃₄N₄O₆
• Purity: Min. 95%
• Molecular weight: 570.6 g/mol

Naldemedine

CAS: 916072-89-4

Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. …

• Formula: C₃₂H₃₄N₄O₆
• Color and Shape: Solid
• Molecular weight: 570.64