CAS 91618-36-9

Ibafloxacin

Description:

Ibafloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative and some Gram-positive organisms. The compound exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Ibafloxacin is known for its favorable pharmacokinetic properties, including good oral bioavailability and tissue penetration, which enhance its therapeutic efficacy. The substance typically presents as a white to off-white crystalline powder, and it is soluble in organic solvents while having limited solubility in water. Its chemical structure includes a bicyclic core with a fluorine atom, which contributes to its potency and resistance to bacterial efflux mechanisms. As with other fluoroquinolones, caution is advised regarding potential side effects, including tendonitis and effects on cartilage development, particularly in pediatric populations. Overall, Ibafloxacin represents a valuable option in the arsenal of antibiotics for treating bacterial infections.

Formula: C₁₅H₁₄FNO₃

InChI: InChI=1/C15H14FNO3/c1-7-3-4-9-8(2)12(16)5-10-13(9)17(7)6-11(14(10)18)15(19)20/h5-7H,3-4H2,1-2H3,(H,19,20)

InChI key: InChIKey=DXKRGNXUIRKXNR-UHFFFAOYSA-N

SMILES: O=C1C=2C=3N(C=C1C(O)=O)C(C)CCC3C(C)=C(F)C2

Synonyms:

• 1H,5H-benzo[ij]quinolizine-2-carboxylic acid, 9-fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-
• 9-Fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid
• 9-fluoro-5,8-dimethyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
• 91618-36-9
• Ibaflin
• R 835
• S 25930
• Ibafloxacin
• 6,7-Dihydro-9-fluoro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid
• R835
• Ibafloxacine

Ibafloxacine

CAS: 91618-36-9

Formula: C₁₅H₁₄FNO₃

Molecular weight: 275.28

Ref: 4Z-I-081001

Ibafloxacin

CAS: 91618-36-9

Ibafloxacin is an antibacterial agent, which is a synthetic fluoroquinolone derived from quinolone compounds. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription in bacteria. By preventing the supercoiling and uncoiling of bacterial DNA, ibafloxacin disrupts essential DNA processes, leading to bacterial cell death.

Formula: C₁₅H₁₄FNO₃

Purity: Min. 95%

Molecular weight: 275.27 g/mol

Ref: 3D-RDA61836

Ibafloxacine

CAS: 91618-36-9

Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against

Formula: C₁₅H₁₄FNO₃

Purity: 97.67%

Color and Shape: Solid

Molecular weight: 275.27

Ref: TM-T12649