CAS 916591-01-0

(4S,7R)-1-(2,4-Difluorophenyl)-N-(1,1-dimethylethyl)-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-3-carboxamide

Description:

The chemical substance with the name "(4S,7R)-1-(2,4-Difluorophenyl)-N-(1,1-dimethylethyl)-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-3-carboxamide" and CAS number "916591-01-0" is a synthetic compound characterized by its complex structure, which includes a tetrahydro-indazole core and a difluorophenyl substituent. This compound features stereocenters, indicated by the (4S,7R) configuration, which contributes to its potential biological activity and specificity. The presence of the difluorophenyl group suggests enhanced lipophilicity and potential interactions with biological targets, while the carboxamide functional group may influence solubility and reactivity. Such compounds are often investigated for their pharmacological properties, including potential therapeutic applications in various diseases. The specific stereochemistry and functional groups present in this molecule can significantly affect its binding affinity and efficacy in biological systems, making it a subject of interest in medicinal chemistry and drug development.

Formula: C₁₉H₂₁F₂N₃O

InChI: InChI=1S/C19H21F2N3O/c1-19(2,3)22-18(25)16-15-10-4-5-11(8-10)17(15)24(23-16)14-7-6-12(20)9-13(14)21/h6-7,9-11H,4-5,8H2,1-3H3,(H,22,25)/t10-,11+/m0/s1

InChI key: InChIKey=NTPZXHMTJGOMCJ-WDEREUQCSA-N

SMILES: C(NC(C)(C)C)(=O)C=1C2=C(N(N1)C3=C(F)C=C(F)C=C3)[C@]4(C[C@@]2(CC4)[H])[H]

Synonyms:

• (4S,7R)-1-(2,4-Difluorophenyl)-N-(1,1-dimethylethyl)-4,5,6,7-tetrahydro-4,7-methano-1H-indazole-3-carboxamide
• Tedalinab
• 4,7-Methano-1H-indazole-3-carboxamide, 1-(2,4-difluorophenyl)-N-(1,1-dimethylethyl)-4,5,6,7-tetrahydro-, (4S,7R)-

Tedalinab

Controlled Product

CAS: 916591-01-0

Applications Tedalinab is a cannabinoid receptor modulator that is useful for treating non-immediate type allergic diseases.
References Muthuppalaniappan, M., et al.: PCT Int. Appl. WO 2006129178 A1 20061207. Dec 7, 2006; Narayanan, S., et al.: U.S. Pat. Appl. Publ. US 20090312385 A1 20091217. Dec 17, 2009

Formula: C₁₉H₂₁F₂N₃O

Color and Shape: Neat

Molecular weight: 345.39

Ref: TR-T013730

Tedalinab-d9

Controlled Product

CAS: 916591-01-0

Formula: C₁₉D₉H₁₂F₂N₃O

Color and Shape: Neat

Molecular weight: 354.442

Ref: TR-T013732

Tedalinab

CAS: 916591-01-0

Tedalinab is an effective and selective cannabinoid receptor 2 agonist.

Formula: C₁₉H₂₁F₂N₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 345.39

Ref: TM-T17027