CAS 916599-27-4

Prasugrel Metabolite M5

Description:

Prasugrel Metabolite M5, identified by the CAS number 916599-27-4, is a significant metabolite of the antiplatelet medication prasugrel, which is used to reduce the risk of cardiovascular events in patients undergoing procedures like percutaneous coronary intervention. This metabolite is formed through the metabolic conversion of prasugrel in the liver, primarily via cytochrome P450 enzymes. Characteristically, M5 exhibits a different pharmacological profile compared to its parent compound, with implications for its efficacy and safety in clinical settings. It is known to retain some antiplatelet activity, contributing to the overall therapeutic effects of prasugrel. The chemical structure of M5 includes functional groups that influence its solubility, stability, and interaction with biological targets. Understanding the characteristics of this metabolite is crucial for assessing the pharmacokinetics and pharmacodynamics of prasugrel therapy, as well as for evaluating potential drug-drug interactions and individual patient responses to treatment.

Formula: C₁₉H₂₂FNO₃S

Synonyms:

• R-106583 (Prasugrel Metabolite)
• 2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-(Methylthio)-3-piperidinylidene]acetic Acid
• Prasugrel Metabolite M5 (R106583)
• Prasugrel metabolite R-106583 (mixture of diastereoisomer)
• Prasugrel Inactive Metabolite R106583 (Mixture of Diastereomers)
• Prasugrel metabolite R106583 hydrochloride salt (Mixture of diastereoisomers)
• (2Z)-2-[1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-methylsulfanylpiperidin-3-ylidene]acetic acid
• Prasugrel Metabolite M5
• Prasugrel Metabolite (R-106583, Mixture of Diastereomers)
• R 106583
• Prasugrel Metabolite (R-106583)
• Prasugrel Impurity N

Prasugrel Metabolite (R-106583)-d3

CAS: 916599-27-4

Formula: C₁₉H₁₉FNO₃SD₃

Molecular weight: 366.47

Ref: 4Z-P-3951

Prasugrel Metabolite (R-106583, Mixture of Diastereomers)

CAS: 916599-27-4

Formula: C₁₉H₂₂FNO₃S

Molecular weight: 363.45

Ref: 4Z-P-3959

R-106583 (Prasugrel Metabolite)

Controlled Product

CAS: 916599-27-4

Formula: C₁₉H₂₂FNO₃S

Color and Shape: Neat

Molecular weight: 363.446

Ref: TR-R070150

2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-(methylthio)-3-piperidinylidene]acetic acid

CAS: 916599-27-4

2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-(methylthio)-3-piperidinylidene]acetic acid is an inhibitor of protein kinases that has shown promising results in the treatment of cancer. This compound has been found to induce apoptosis, or programmed cell death, in cancer cells by targeting specific kinases involved in tumor growth and survival. Additionally, studies have shown that 2-[1-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-(methylthio)-3-piperidinylidene]acetic acid can inhibit the growth of tumors in human models. This compound can be detected in urine samples after administration, and its absorption can be enhanced by co-administration with D-xylose. Overall, this anticancer agent shows great potential for the development of novel cancer therapies.

Formula: C₁₉H₂₂FNO₃S

Purity: Min. 95%

Molecular weight: 363.4 g/mol

Ref: 3D-RLB59927

Prasugrel Impurity 18

CAS: 916599-27-4

Formula: C₁₉H₂₂FNO₃S

Molecular weight: 363.45

Ref: ST-EA-CP-P27040