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CAS 917-54-4

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Methyllithium

Description:
Methyllithium is an organolithium compound with the chemical formula CH3Li. It is a colorless, highly reactive solid or liquid at room temperature, depending on its concentration and the presence of solvents. Methyllithium is known for its strong nucleophilic properties, making it a valuable reagent in organic synthesis, particularly for the formation of carbon-carbon bonds. It reacts vigorously with water and moisture, producing methane and lithium hydroxide, which necessitates careful handling under anhydrous conditions. The compound is typically stored in inert atmospheres, such as argon or nitrogen, to prevent decomposition. Methyllithium can also act as a strong base, capable of deprotonating weak acids. Its reactivity allows it to participate in various reactions, including alkylation and the formation of organometallic intermediates. Due to its hazardous nature, including flammability and toxicity, appropriate safety precautions are essential when working with methyllithium in laboratory settings.
Formula:CH3Li
InChI:InChI=1S/CH3.Li/h1H3;
InChI key:InChIKey=DVSDBMFJEQPWNO-UHFFFAOYSA-N
SMILES:C[Li]
Synonyms:
  • Lithium methide
  • Methyl lithium
  • Methyllithium
  • Metillitio
  • MethyllithiumcomplexedwithlithiumbromideinethyletherMc
  • ML-DEE
  • Lithium, methyl-
  • Methyllithium solution
  • Methyllithium lithium bromide complex solution
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