Lexibulin, identified by its CAS number 917111-44-5, is a synthetic compound that belongs to the class of small-molecule inhibitors. It is primarily recognized for its role as an antitumor agent, exhibiting properties that interfere with microtubule dynamics, which are crucial for cell division. Lexibulin's mechanism of action involves binding to tubulin, thereby disrupting the normal function of the mitotic spindle during cell division, leading to apoptosis in cancer cells. This compound has been studied for its potential efficacy against various types of cancer, including solid tumors. In terms of its physical and chemical properties, Lexibulin is characterized by its specific molecular structure, which contributes to its biological activity. The compound is typically evaluated for its pharmacokinetics, toxicity, and overall therapeutic index in preclinical and clinical studies. As with many investigational drugs, ongoing research aims to better understand its full potential and optimize its use in cancer therapy.

Lexibulin

917111-44-5: Lexibulin, identified by its CAS number 917111-44-5, is a synthetic compound that belongs to the class of small-molecule inhibitors. It is primarily recognized for its role as an antitumor agent, exhibiting properties that interfere with microtubule dynamics, which are crucial for cell division. Lexibulin's mechanism of action involves binding to tubulin, thereby disrupting the normal function of the mitotic spindle during cell division, leading to apoptosis in cancer cells. This compound has been studied for its potential efficacy against various types of cancer, including solid tumors. In terms of its physical and chemical properties, Lexibulin is characterized by its specific molecular structure, which contributes to its biological activity. The compound is typically evaluated for its pharmacokinetics, toxicity, and overall therapeutic index in preclinical and clinical studies. As with many investigational drugs, ongoing research aims to better understand its full potential and optimize its use in cancer therapy.

Urea, N-​ethyl-​N'-​[2-​methoxy-​4-​[5-​methyl-​4-​[[(1S)​-​1-​(3-​pyridinyl)​butyl]​amino]​-​2-​pyrimidinyl]​phenyl]​-

<p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>

CAS 917111-44-5

Lexibulin

Urea, N-ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]-

Ref: IN-DA00GU8R

Lexibulin

Ref: 54-BUP07130

Lexibulin

Ref: TM-T2090

CAS 917111-44-5

Lexibulin

Urea, N-​ethyl-​N'-​[2-​methoxy-​4-​[5-​methyl-​4-​[[(1S)​-​1-​(3-​pyridinyl)​butyl]​amino]​-​2-​pyrimidinyl]​phenyl]​-

Ref: IN-DA00GU8R

Lexibulin

Ref: 54-BUP07130

Lexibulin

Ref: TM-T2090

Urea, N-ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]-