CAS 917111-49-0

Urea, N-ethyl-N′-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]-, hydrochloride (1:2)

Description:

Urea, N-ethyl-N′-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]-, hydrochloride (1:2), identified by CAS number 917111-49-0, is a chemical compound characterized by its complex structure, which includes multiple functional groups such as urea, pyrimidine, and aromatic rings. This compound is typically a white to off-white solid and is soluble in water due to the presence of the hydrochloride salt form, which enhances its solubility and bioavailability. The presence of the ethyl and pyridinyl groups suggests potential biological activity, making it of interest in pharmaceutical research. Its molecular structure indicates that it may interact with various biological targets, potentially influencing pathways related to cell signaling or enzyme activity. As a hydrochloride salt, it is often used in formulations to improve stability and handling properties. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₂₄H₃₀N₆O₂·2ClH

InChI: InChI=1S/C24H30N6O2.2ClH/c1-5-8-19(18-9-7-12-25-15-18)28-22-16(3)14-27-23(30-22)17-10-11-20(21(13-17)32-4)29-24(31)26-6-2;;/h7,9-15,19H,5-6,8H2,1-4H3,(H2,26,29,31)(H,27,28,30);2*1H/t19-;;/m0../s1

InChI key: InChIKey=HGDCRTLMRFHNOZ-TXEPZDRESA-N

SMILES: O(C)C=1C=C(C=CC1NC(NCC)=O)C=2N=C(N[C@@H](CCC)C=3C=CC=NC3)C(C)=CN2.Cl

Synonyms:

• Urea, N-ethyl-N′-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]-, hydrochloride (1:2)
• Lexibulin hydrochloride

Lexibulin dihydrochloride

CAS: 917111-49-0

Lexibulin dihydrochloride is a research tool for the study of protein interactions. It is an inhibitor of Protein Kinase C (PKC) that has been shown to regulate the activity of ion channels, such as calcium channels and sodium channels. Lexibulin dihydrochloride is a high-purity chemical compound with a CAS number of 917111-49-0.

Formula: C₂₄H₃₂Cl₂N₆O₂

Purity: Min. 95%

Molecular weight: 507.5 g/mol

Ref: 3D-SLB11149

Lexibulin dihydrochloride

CAS: 917111-49-0

Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.

Formula: C₂₄H₃₂Cl₂N₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 507.46

Ref: TM-T15746