CAS 917392-54-2

Benzoic acid, 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-, methyl ester

Description:

Benzoic acid, 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-, methyl ester, identified by CAS number 917392-54-2, is a complex organic compound characterized by its aromatic structure and functional groups. It features a benzoic acid core with a methyl ester group, which enhances its lipophilicity and solubility in organic solvents. The presence of a pyridine and a pyrimidine moiety contributes to its potential biological activity, making it of interest in medicinal chemistry. This compound may exhibit properties such as antimicrobial or anti-inflammatory effects, although specific biological activities would depend on its interaction with various biological targets. Its molecular structure suggests it could participate in hydrogen bonding and π-π stacking interactions, which are significant in biological systems. Additionally, the compound's stability and reactivity can be influenced by the substituents on the aromatic rings, making it a candidate for further research in drug development and synthesis. Safety and handling precautions should be observed, as with any chemical substance, due to potential toxicity or reactivity.

Formula: C₁₈H₁₆N₄O₂

InChI: InChI=1/C18H16N4O2/c1-12-5-6-13(17(23)24-2)10-16(12)22-18-20-9-7-15(21-18)14-4-3-8-19-11-14/h3-11H,1-2H3,(H,20,21,22)

InChI key: InChIKey=BECBKQYLJDEVDN-UHFFFAOYSA-N

SMILES: N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=CC(C(OC)=O)=CC=C3C

Synonyms:

• 4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Benzoic Acid Methyl Ester
• Benzoic acid,4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-,methyl ester
• Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate
• 4-Methyl-3-(4-pyridin-3-yl-pyriMidin-2-ylaMino)-benzoic acid Methyl ester
• NILOTINIB EP IMPURITY G
• Methyl 4-Methyl-3-((4-(pyridin-3-yl)pyriMidin-2-yl)aMino)benzoate, Methyl 4-Methyl-3-(4-(pyridin-3-yl)pyriMidin-2-ylaMino)benzoate
• Benzoicacid, 4-Methyl-3-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-, Methyl ester
• methyl 4-methyl-3-[[4-(3-pyridyl)pyrimidin-2-yl]amino]benzoate

Nilotinib Related Compound D

CAS: 917392-54-2

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₁₈H₁₆N₄O₂

Color and Shape: Yellow Yellowish-Brown Solid

Molecular weight: 320.12733

Ref: 45-1463458

Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

CAS: 917392-54-2

Formula: C₁₈H₁₆N₄O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 320.3452

Ref: IN-DA0036YM

Nilotinib EP Impurity G

CAS: 917392-54-2

Formula: C₁₈H₁₆N₄O₂

Color and Shape: Off-White Solid

Molecular weight: 320.35

Ref: 4Z-N-3128

Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

CAS: 917392-54-2

Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 320.35g/mol

Ref: 54-OR350263

Methyl 4-Methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate

CAS: 917392-54-2

Color and Shape: Neat

Ref: 86-MM3374.20

Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate

CAS: 917392-54-2

Purity: 95+%

Molecular weight: 320.35198974609375

Ref: 10-F724008

Nilotinib EP Impurity G

CAS: 917392-54-2

Formula: C₁₈H₁₆N₄O₂

Molecular weight: 320.35

Ref: ST-EA-CP-N11007

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoicacid methylester

CAS: 917392-54-2

4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoicacid methylester is a fine chemical that is useful as a scaffold for more complex compounds and has many other uses. It is a versatile building block, useful intermediate and research chemical, reaction component, speciality chemical, and building block. This compound can be used to make high quality reagents with many applications in medicine, chemistry, and biology.

Formula: C₁₈H₁₆N₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 320.35 g/mol

Ref: 3D-FM151656

Methyl 4-Methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate

Controlled Product

CAS: 917392-54-2

Applications Methyl 4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzoate is an intermediate used in the synthesis of 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide (M326838), which is an impurity of Nilotinib (N465300), a possible agent in the treatment of chronic myelogenous leukemia.
References Corbin, A., et al.: J. Biol. Chem., 277, 32214 (2002); Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005); Gleixner, K., et al.: Blood, 107, 752 (2006); Nicolini, F., et al.: Leukemia, 20, 1061 (2006)

Formula: C₁₈H₁₆N₄O₂

Color and Shape: Neat

Molecular weight: 320.35

Ref: TR-M325060