CAS 917879-39-1

MK-2461

Description:

MK-2461, also known by its CAS number 917879-39-1, is a chemical compound that has been studied primarily in the context of medicinal chemistry and drug development. It is classified as a small molecule and is known to act as a selective inhibitor of certain biological pathways, particularly those involved in cancer cell proliferation and survival. The compound exhibits specific interactions with target proteins, which can lead to the modulation of cellular processes. MK-2461 has been investigated for its potential therapeutic applications, particularly in oncology, where it may contribute to the treatment of various types of cancer by disrupting tumor growth and enhancing the efficacy of existing therapies. Its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, are critical for determining its suitability as a drug candidate. As with many investigational compounds, ongoing research is essential to fully elucidate its mechanism of action, safety profile, and potential side effects in clinical settings.

Formula: C₂₄H₂₅N₅O₅S

Synonyms:

• N-[(2R)-1,4-dioxan-2-ylMethyl]-N-Methyl{[5-(1-Methyl-1H-pyrazol-4-yl)-2-oxo-7-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-14-yl]aMino}sulfonaMide
• Sulfamide, N-[(2R)-1,4-dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-
• N-[(2R)-1,4-Dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepsulfamide

N-[(2R)-1,4-Dioxan-2-ylmethyl]-N-methyl-N'-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]sulfamide

CAS: 917879-39-1

Formula: C₂₄H₂₅N₅O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 495.5508

Ref: IN-DA0039XN

MK-2461

CAS: 917879-39-1

MK-2461

Purity: ≥95%

Molecular weight: 495.55g/mol

Ref: 54-BUP12526

MK-2461

CAS: 917879-39-1

Ref: 7W-GW5073

MK-2461

Controlled Product

CAS: 917879-39-1

Formula: C₂₄H₂₅N₅O₅S

Color and Shape: Neat

Molecular weight: 495.551

Ref: TR-M425035

MK-2461

CAS: 917879-39-1

MK-2461 is an orally bioavailable small molecule that binds to the epidermal growth factor receptor (EGFR) and inhibits its downstream signaling. It has been shown to have potent antitumor activity in cell culture and in vivo against a range of tumor types. MK-2461 binds to the EGFR with high affinity, inhibiting the downstream signaling pathway by blocking the activation of molecules such as Raf, MEK1/2, and ERK1/2. The binding site of MK-2461 is located on the extracellular domain of EGFR.

Formula: C₂₄H₂₅N₅O₅S

Purity: Min. 95%

Molecular weight: 495.55 g/mol

Ref: 3D-SLB87939

MK-2461

CAS: 917879-39-1

MK-2461 is a novel inhibitor that targets multiple proteins and competitively binds to ATP sites, specifically inhibiting the activated c-Met protein with an

Formula: C₂₄H₂₅N₅O₅S

Purity: 95.41% - 99.53%

Color and Shape: Solid

Molecular weight: 495.55

Ref: TM-T6094