CAS 91797-57-8

(1S,4S)-4-(3,4-dichlorophenyl)tetralin-1-amine hydrochloride

Description:

(1S,4S)-4-(3,4-dichlorophenyl)tetralin-1-amine hydrochloride, with the CAS number 91797-57-8, is a chemical compound characterized by its specific stereochemistry and functional groups. It features a tetralin core, which is a bicyclic structure composed of a benzene ring fused to a cyclohexane ring. The presence of a 3,4-dichlorophenyl group indicates that two chlorine atoms are substituted on the phenyl ring, which can significantly influence the compound's biological activity and lipophilicity. The amine functional group suggests potential for hydrogen bonding and reactivity, while the hydrochloride salt form enhances its solubility in water, making it more suitable for pharmaceutical applications. This compound may exhibit specific pharmacological properties, potentially acting as a ligand for various receptors or enzymes, although detailed biological activity would require further investigation. Overall, its unique structural features contribute to its potential utility in medicinal chemistry and drug development.

Formula: C₁₆H₁₆Cl₃N

InChI: InChI=1/C16H15Cl2N.ClH/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13;/h1-5,7,9,11,16H,6,8,19H2;1H/t11-,16-;/m0./s1

SMILES: c1ccc2c(c1)[C@@H](CC[C@@H]2N)c1ccc(c(c1)Cl)Cl.Cl

Synonyms:

• Norsertraline hydrochloride solution
• cis-(-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine Hydrochloride
• Sertraline N-Desmethyl Impurity
• cis- 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine Hydrochloride

rac-Norsertraline Hydrochloride 0.1 mg/ml in Methanol (as free base)

CAS: 91797-57-8

Color and Shape: Single Solution

Ref: 61-AMP0317.02-02

rac-Norsertraline.HCl, 1mg/ml in Methanol (as free base)

CAS: 91797-57-8

Color and Shape: Single Solution

Ref: LP-SRT-1583-HC-1LM

rac-Norsertraline.HCl

CAS: 91797-57-8

Color and Shape: Neat

Ref: LP-SRT-1583-HC-10

rac-Norsertraline Hydrochloride

CAS: 91797-57-8

Color and Shape: Neat

Ref: 61-FOR0317.02

(±)-cis-N-Desmethylsertraline-1,2,2-d3 HCl

CAS: 91797-57-8

Purity: 98 atom % D

Molecular weight: 331.69

Ref: 3U-D7633

rac-cis-N-Desmethyl Sertraline-d4 Hydrochloride

Controlled Product

CAS: 91797-57-8

Applications A labelled metabolite of Sertraline. N-Desmethyl Sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.
References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)

Formula: C₁₆H₁₂D₄Cl₃N

Color and Shape: Neat

Molecular weight: 332.69

Ref: TR-D292103

rac-cis-N-Desmethyl Sertraline Hydrochloride

Controlled Product

CAS: 91797-57-8

Formula: C₁₆H₁₅Cl₂N·ClH

Color and Shape: White

Molecular weight: 328.66

Ref: TR-D292100

rac-cis-N-Desmethyl sertraline hydrochloride

CAS: 91797-57-8

Rac-cis-N-Desmethyl sertraline hydrochloride is an analog of the antidepressant drug, sertraline. It is a racemic mixture of two stereoisomers that are mirror images of each other and have different effects on the human body. Rac-cis-N-Desmethyl sertraline hydrochloride has been shown to inhibit reuptake of serotonin from the synaptic cleft, which may be responsible for its antidepressant effect. The compound is also radiolabeled with carbon 11 and can be used as a diagnostic agent for positron emission tomography (PET).

Formula: C₁₆H₁₆Cl₃N

Purity: Min. 96 Area-%

Color and Shape: White Powder

Molecular weight: 328.66 g/mol

Ref: 3D-FR27635

rac-cis-N-Desmethyl Sertraline-d3 Hydrochloride

Controlled Product

CAS: 91797-57-8

Applications rac-cis-N-Desmethyl Sertraline-d3 hydrochloride is a labelled metabolite of rac-cis-N-Desmethyl sertraline hydrochloride (D292100). N-Desmethyl sertraline is significantly less active analogue as compared to the methylated compound, sertraline.
References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)

Formula: C₁₆H₁₃D₃Cl₃N

Color and Shape: Neat

Molecular weight: 331.68

Ref: TR-D292104

Sertraline N-Desmethyl Analog

CAS: 91797-57-8

Formula: C₁₆H₁₅Cl₂NHCl

Molecular weight: 292.2 . 36.46

Ref: ST-EA-CP-S6030