CAS 91809-67-5

6-Carboxytetramethylrhodamine

Description:

6-Carboxytetramethylrhodamine (often abbreviated as TMR or TMR carboxylic acid) is a fluorescent dye commonly used in biological and chemical research. It belongs to the rhodamine family of dyes, characterized by their vibrant fluorescence and stability. This compound features a carboxylic acid functional group, which enhances its solubility in aqueous solutions, making it suitable for various applications, including labeling biomolecules and imaging in live cells. The dye exhibits strong absorption and emission properties, typically in the green to red spectrum, allowing for effective visualization under fluorescence microscopy. Its high quantum yield and photostability make it a preferred choice for fluorescence-based assays. Additionally, the presence of the carboxylic acid group allows for conjugation with other molecules, facilitating its use in bioconjugation techniques. Overall, 6-Carboxytetramethylrhodamine is valued for its versatility and effectiveness in a wide range of scientific applications, particularly in the fields of biochemistry and molecular biology.

Formula: C₂₅H₂₂N₂O₅

InChI: InChI=1S/C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31/h5-13H,1-4H3,(H-,28,29,30,31)

InChI key: InChIKey=COCMHKNAGZHBDZ-UHFFFAOYSA-N

SMILES: C([O-])(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(N(C)C)=C4)C=C(N(C)C)C=C3)C=C(C(O)=O)C=C1

Synonyms:

• 4-carboxy-3-[6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]benzoate
• 6-Carboxy-Tetramethylrhodamine, For Fluorescence
• 6-Tamra
• N,N,N′,N′-Tetramethyl-6-carboxyrhodamine
• Xanthylium, 9-(2,5-dicarboxyphenyl)-3,6-bis(dimethylamino)-, inner salt
• 6-Carboxytetramethylrhodamine

6-Carboxytetramethylrhodamine

CAS: 91809-67-5

Formula: C₂₅H₂₂N₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 430.4526

Ref: IN-DA00GRM2

6-TAMRA

CAS: 91809-67-5

6-TAMRA

Purity: ≥98%

Molecular weight: 430.45g/mol

Ref: 54-BUP11089

6-Carboxytetramethylrhodamine

CAS: 91809-67-5

6-Carboxytetramethylrhodamine

Color and Shape: Powder

Molecular weight: 430.45g/mol

Ref: 54-BIB6288

6-Carboxytetramethylrhodamine

CAS: 91809-67-5

Formula: C₂₅H₂₂N₂O₅

Purity: ≥ 90.0%

Color and Shape: Black powder

Molecular weight: 430.45

Ref: 7W-GT0256

6-TAMRA

CAS: 91809-67-5

6-TAMRA (6-Carboxytetramethylrhodamine) serves as a popular fluorophore for the creation of bioconjugates, particularly in the synthesis of fluorescent

Formula: C₂₅H₂₂N₂O₅

Purity: 98.23%

Color and Shape: Solid

Molecular weight: 430.45

Ref: TM-T18905

6-Carboxytetramethylrhodamine

CAS: 91809-67-5

6-Carboxytetramethylrhodamine is a fine chemical that is used as a building block in the synthesis of other compounds. It has been used in research to study protein function and in the development of new drugs. 6-Carboxytetramethylrhodamine may be used as an intermediate or scaffold for complex molecules, and has been applied as a reagent in the study of DNA. Its versatility makes it a useful building block for many applications.

Formula: C₂₅H₂₂N₂O₅

Purity: Min. 80 Area-%

Molecular weight: 430.45 g/mol

Ref: 3D-J-100076

6-Carboxytetramethyl rhodamine

CAS: 91809-67-5

6-Carboxytetramethyl rhodamine is a fluorescent dye that is used to measure the presence of cancer cells in urine samples. It binds to human protein and has been shown to be a useful probe for fluorescence measurements. 6-Carboxytetramethyl rhodamine has also been used as a fluorescence probe for the detection of proliferative diabetic retinopathy and michaelis–menten kinetics in cyclic peptides.

Formula: C₂₅H₂₂N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 430.45 g/mol

Ref: 3D-FC19807

6-Carboxy-tetramethylrhodamine

CAS: 91809-67-5

Formula: C₂₅H₂₂N₂O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 430.46

Ref: 10-F541470

6-Carboxytetramethyl rhodamine hydrochloride

CAS: 91809-67-5

6-Carboxytetramethyl rhodamine hydrochloride is a fluorescent probe that produces an intense red fluorescence when bound to nucleic acids and proteins. The fluorescence can be measured using a spectrofluorimeter, which is a device that measures the intensity of light emitted by cells in response to excitation by an ultraviolet or visible light source. 6-Carboxytetramethyl rhodamine hydrochloride has been used as a fluorescent probe for the detection of human protein in x-ray crystal structures. This probe has also been used to detect herpes simplex virus (HSV) and other DNA viruses. The basic properties of this compound are determined by its sequence and structure, which can be studied using molecular methods such as hybridization or proximal tubule analysis.

Formula: C₂₅H₂₂N₂O₅·HCl

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 466.91 g/mol

Ref: 3D-FC171265