CAS 918505-84-7

N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

Description:

N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide, with CAS number 918505-84-7, is a synthetic organic compound characterized by its complex structure, which includes a sulfonamide functional group, a pyrrolopyridine moiety, and multiple fluorine substituents. This compound typically exhibits properties such as high solubility in polar solvents, which is common for sulfonamides, and may demonstrate biological activity due to its structural features. The presence of the chloro and difluoro groups can influence its reactivity and interaction with biological targets, potentially enhancing its pharmacological profile. As a sulfonamide, it may also exhibit antibacterial properties, although specific biological activities would depend on further empirical studies. The compound's molecular structure suggests potential applications in medicinal chemistry, particularly in the development of targeted therapies. Safety and handling precautions should be observed, as with all chemical substances, due to the potential for toxicity and environmental impact.

Formula: C₁₇H₁₄ClF₂N₃O₃S

InChI: InChI=1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22)

InChI key: InChIKey=YZDJQTHVDDOVHR-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(NC1)=NC=C(Cl)C2)C3=C(F)C(NS(CCC)(=O)=O)=CC=C3F

Synonyms:

• 1-Propanesulfonamide, N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-
• N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide
• Plx-4720

PLX-4720

CAS: 918505-84-7

PLX-4720

Purity: ≥95%

Molecular weight: 413.83g/mol

Ref: 54-BUP11952

PLX-4720

CAS: 918505-84-7

PLX-4720 is a potent and selective B-Raf (V600E) inhibitor designed to block the ATP-binding site of oncogenic B-Raf.Cost-effective and quality-assured.

Formula: C₁₇H₁₄ClF₂N₃O₃S

Purity: 97.78% - 99.83%

Color and Shape: Solid

Molecular weight: 413.83

Ref: TM-T2473

PLX4720

CAS: 918505-84-7

Formula: C₁₇H₁₄ClF₂N₃O₃S

Molecular weight: 413.8

Ref: 7W-GL9916

PLX 4720

CAS: 918505-84-7

Inhibitor of B-RAF kinase

Formula: C₁₇H₁₄O₃N₃SF₂Cl

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 413.04125

Ref: 3D-FC34125