CAS 91912-53-7

3-(pyridin-4-yl)-1H-pyrazol-5-amine

Description:

3-(Pyridin-4-yl)-1H-pyrazol-5-amine, with the CAS number 91912-53-7, is an organic compound characterized by its pyrazole and pyridine functional groups. This compound features a pyrazole ring, which is a five-membered ring containing two adjacent nitrogen atoms, and a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. The presence of the amino group (-NH2) at the 5-position of the pyrazole contributes to its potential as a building block in medicinal chemistry and drug development. The compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amino group. Its structure suggests potential biological activity, making it of interest in various fields, including pharmaceuticals and agrochemicals. Additionally, the compound may participate in hydrogen bonding and other intermolecular interactions, influencing its reactivity and interactions with biological targets. Overall, 3-(pyridin-4-yl)-1H-pyrazol-5-amine is a versatile compound with potential applications in research and industry.

Formula: C₈H₈N₄

InChI: InChI=1/C8H8N4/c9-8-5-7(11-12-8)6-1-3-10-4-2-6/h1-5H,(H3,9,11,12)

SMILES: c1cnccc1c1cc(=N)[nH][nH]1

Synonyms:

• 1H-pyrazol-5-amine, 3-(4-pyridinyl)-
• 5-(4-pyridinyl)-1H-pyrazol-3-amine(SALTDATA: 1.3HCl)
• 3-Amino-5-(4-pyridyl)-1H-pyrazole
• 5-PYRIDIN-4-YL-2H-PYRAZOL-3-YLAMINE
• 3-Amino-5-(pyridin-4-yl)-1H-pyrazole
• 5-(4-pyridinyl)- 1H-Pyrazol-3-amine
• 1H-Pyrazol-3-amine, 5-(4-pyridinyl)-
• 5-(pyridin-4-yl)-1H-pyrazol-3-aMine

3-(Pyridin-4-yl)-1H-pyrazol-5-amine

CAS: 91912-53-7

Formula: C₈H₈N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 160.1759

Ref: IN-DA0038JF

5-(4-Pyridinyl)-1H-pyrazol-3-amine

CAS: 91912-53-7

5-(4-Pyridinyl)-1H-pyrazol-3-amine

Purity: 98%

Molecular weight: 160.18g/mol

Ref: 54-OR76128

5-Pyridin-4-yl-2H-pyrazol-3-ylamine

CAS: 91912-53-7

Formula: C₈H₈N₄

Purity: 98%

Molecular weight: 160.18

Ref: 10-F225244

5-Pyridin-4-yl-2H-pyrazol-3-ylamine

CAS: 91912-53-7

5-Pyridin-4-yl-2H-pyrazol-3-ylamine is a potent inhibitor of b-raf, a protein kinase that is involved in the regulation of cell proliferation and differentiation. It is used as a research tool for studying the role of b-raf in cancer. 5-Pyridin-4-yl-2H-pyrazol-3-ylamine has been shown to have similar activity to other inhibitors of bRaf. It binds to the ATP binding site on bRaf and prevents phosphorylation of serine residues in the activation loop by ATP. This inhibition prevents activation of the kinase and reduces tumor growth in cancer models.

Formula: C₈H₈N₄

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 160.18 g/mol

Ref: 3D-FP51268