CAS 91917-63-4

atrial natriuretic peptide human

Description:

Atrial natriuretic peptide (ANP) is a peptide hormone primarily produced by the atrial cells of the heart in response to increased blood volume and pressure. It plays a crucial role in regulating blood pressure and fluid balance. ANP functions by promoting natriuresis, the excretion of sodium through urine, which leads to increased urine output and a reduction in blood volume. This mechanism helps to lower blood pressure. The peptide is composed of 28 amino acids and is characterized by its ability to bind to specific receptors, triggering intracellular signaling pathways that result in vasodilation and inhibition of renin and aldosterone secretion. ANP is also involved in various physiological processes, including the modulation of cardiovascular function and electrolyte homeostasis. Its therapeutic potential is being explored in conditions such as heart failure and hypertension. The CAS number 91917-63-4 uniquely identifies this specific form of human atrial natriuretic peptide, facilitating its study and application in biomedical research and clinical settings.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Synonyms:

• Atrial Natriuretic Factor 1-28, Human
• Anp 1-28, Human
• SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR(DISULFIDE BRIDGE:CYS7-CYS23)

Atrial natriuretic peptide-28 (human reduced)

CAS: 91917-63-4

Formula: C₁₂₇H₂₀₅N₄₅O₃₉S₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 3082.4597

Ref: IN-DA00GSXZ

ANP (Human, 1-28)

CAS: 91917-63-4

ANP (Human, 1-28) is a peptide with the sequence of amino acids 1-28 of the human atrial natriuretic peptide. ANP (Human, 1-28) is an activator of the receptor for ANP which belongs to the G protein coupled receptor superfamily. This peptide has been shown to inhibit ion channels and ligands and can be used as a research tool in cell biology, such as cell culture and immunohistochemistry.

Purity: Min. 95%

Ref: 3D-PAF-4135-V

ANP (Human, 1-28)

CAS: 91917-63-4

ANP (1-28) is a peptide that is secreted by the human heart and has been shown to act as an inhibitor of ion channels and receptors. ANP (1-28) binds to the receptor, which then changes its shape. The receptor then becomes more sensitive to other ligands and it can activate or inhibit cell signaling pathways. ANP (1-28) also binds to antibodies that are used in research tools for cell biology, pharmacology, and protein interactions. This peptide has a high purity level of > 95% with a CAS number of 91917-63-4.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Purity: Min. 95%

Molecular weight: 3,080.4 g/mol

Ref: 3D-PAF-4135-S

[Met(O)12]-ANP (Human, 1-28)

CAS: 91917-63-4

[Met(O)12]-ANP (Human, 1-28) is a peptide that activates the guanylate cyclase. It has been shown to bind to the receptor for ANP, which is present in many cell types. The binding of [Met(O)12]-ANP (Human, 1-28) to its receptor leads to an increase in intracellular cGMP levels and consequently an increase in intracellular cAMP levels. This product is a research tool for protein interactions and can be used as an inhibitor or activator. The purity of this product is >98%.

Formula: C₁₂₇H₂₀₃N₄₅O₄₀S₃

Purity: Min. 95%

Molecular weight: 3,096.4 g/mol

Ref: 3D-PAF-4145-V

α-ANF(1-28), human

CAS: 91917-63-4

Custom research peptide; min purity 95%.

Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Purity: Min. 95%

Molecular weight: 3,080.46 g/mol

Ref: 3D-PA17124