CAS 91917-65-6

Ethyl 8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

Description:

Ethyl 8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate is a complex organic compound characterized by its unique bicyclic structure, which incorporates both imidazole and benzodiazepine moieties. The presence of an azido group (-N3) contributes to its potential reactivity, making it of interest in various synthetic applications, particularly in the field of medicinal chemistry. The ethyl ester functional group enhances its solubility and bioavailability, which is crucial for pharmacological studies. This compound may exhibit biological activity due to its structural features, potentially influencing various biochemical pathways. Its synthesis typically involves multi-step reactions, requiring careful control of conditions to ensure the stability of the azido group and the integrity of the bicyclic framework. As with many azido compounds, safety precautions are necessary due to the potential for explosive decomposition under certain conditions. Overall, this compound represents a fascinating intersection of organic synthesis and medicinal chemistry, with implications for drug development and research.

Formula: C₁₅H₁₄N₆O₃

InChI: InChI=1S/C15H14N6O3/c1-3-24-15(23)13-12-7-20(2)14(22)10-6-9(18-19-16)4-5-11(10)21(12)8-17-13/h4-6,8H,3,7H2,1-2H3

InChI key: InChIKey=CFSOJZTUTOQNIA-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C1=C2N(C=3C(=CC(N=[N+]=[N-])=CC3)C(=O)N(C)C2)C=N1

Synonyms:

• 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-azido-5,6-dihydro-5-methyl-6-oxo-, ethyl ester
• Ethyl 8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
• Ro 15-4513

Ro 15-4513

CAS: 91917-65-6

Formula: C₁₅H₁₄N₆O₃

Purity: ≥ 95.0%

Color and Shape: Yellow powder or solid

Molecular weight: 326.31

Ref: 7W-GL9466

Ro 15-4513

Controlled Product

CAS: 91917-65-6

Formula: C₁₅H₁₄N₆O₃

Color and Shape: Neat

Molecular weight: 326.31

Ref: TR-R700943

Ro15-4513

CAS: 91917-65-6

Ro15-4513 is a drug that binds to the benzodiazepine receptor on the GABA receptor complex. It enhances the uptake of GABA and increases its effect on the GABA A receptors, which are inhibitory receptors in the central nervous system. Ro15-4513 has also been shown to increase locomotor activity and enhance benzodiazepine binding in rats with cerebellar purkinje neurons. The experimental model used for this study was an α1 subunit knockout mouse. The α1 subunit is an important part of the benzodiazepine receptor complex and plays a role in regulating the effects of these drugs, such as sedation, muscle relaxation, and anti-convulsant properties.

Formula: C₁₅H₁₄N₆O₃

Purity: Min. 95%

Molecular weight: 326.31 g/mol

Ref: 3D-RDA91765

Ro15-4513

CAS: 91917-65-6

Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.

Formula: C₁₅H₁₄N₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 326.31

Ref: TM-T16775