CAS 919346-89-7

5-Bromo-2,3-dihydro-1H-Isoindole Hydrochloride

Description:

5-Bromo-2,3-dihydro-1H-isoindole hydrochloride is a chemical compound characterized by its isoindole structure, which features a bicyclic system comprising a five-membered ring fused to a six-membered ring. The presence of a bromine atom at the 5-position contributes to its reactivity and potential applications in organic synthesis and medicinal chemistry. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, enhancing its utility in biological studies and pharmaceutical formulations. This compound may exhibit various biological activities, making it of interest in drug discovery and development. Its molecular properties, such as melting point, solubility, and stability, can vary based on environmental conditions and the presence of other substances. Safety data should be consulted to understand its handling and potential hazards, as with any chemical compound. Overall, 5-Bromo-2,3-dihydro-1H-isoindole hydrochloride represents a versatile building block in synthetic organic chemistry.

Formula: C₈H₉BrClN

InChI: InChI=1/C8H8BrN.ClH/c9-8-2-1-6-4-10-5-7(6)3-8;/h1-3,10H,4-5H2;1H

SMILES: c1cc(cc2CNCc12)Br.Cl

5-Bromo-2,3-dihydro-1h-isoindole, HCl

CAS: 919346-89-7

Formula: C₈H₉BrClN

Purity: 97%

Color and Shape: Solid

Molecular weight: 234.5208

Ref: IN-DA0038JD

5-Bromoisoindoline hydrochloride

CAS: 919346-89-7

5-Bromoisoindoline hydrochloride

Formula: C₈H₈BrN·ClH

Purity: 97%

Color and Shape: grey solid

Molecular weight: 234.52g/mol

Ref: 54-OR450024

5-Bromo-isoindoline hydrochloride

CAS: 919346-89-7

Formula: C₈H₉BrClN

Purity: 97%

Color and Shape: Solid

Molecular weight: 234.52

Ref: 10-F048782

5-Bromoisoindoline Hydrochloride

Controlled Product

CAS: 919346-89-7

Applications 5-Bromoisoindoline Hydrochloride acts as a reagent in the preparation of cyanopyrrolidines as DUB inhibitors for the treatment of cancer, preparation of oxazolidinone containing fused ring as antibiotics, preparation of novel indolecarboxamides as IKK2 inhibitors. Also a derivative salt of 5-Bromoisoindoline Hydrochloride (B683270), which is an intermediate used in the synthesis of 2,3-dihydro-1H-isoindoles with high affinity and selectivity for dopamine D3 receptor.
References Austin, N., et al.: Bioorg. Med. Chem. Lett., 11, 685 (2001); Kemp, M., et al.: PCT Int. Appl. (2017), WO 2017009650 A1 20170119; Zhang, H., et al.: PCT Int. Appl. (2013), WO 2013044865 A1 20130404; Deng, J., et al.: U.S. Pat. Appl. Publ. (2009), US 20090143372 A1 20090604

Formula: C₈H₈BrN•hCi

Color and Shape: Neat

Molecular weight: 198.063646

Ref: TR-B678895