CAS 91940-87-3

2H-3-Benzazepin-2-one, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-, hydrochloride (1:1)

Description:

2H-3-Benzazepin-2-one, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-, hydrochloride (1:1), identified by CAS number 91940-87-3, is a complex organic compound characterized by its multi-ring structure that includes a benzazepine core. This compound features a tetrahydro configuration, indicating the presence of a saturated ring system, and is substituted with methoxy groups, which enhance its lipophilicity and potentially influence its biological activity. The presence of a hydrochloride salt form suggests improved solubility in aqueous environments, which is often beneficial for pharmacological applications. The compound's structure includes various functional groups, such as amines and ethers, which may contribute to its reactivity and interaction with biological targets. Overall, this substance is of interest in medicinal chemistry, particularly for its potential therapeutic effects, although specific biological activities and mechanisms would require further investigation through empirical studies.

Formula: C₂₆H₃₆N₂O₅·ClH

InChI: InChI=1S/C26H36N2O5.ClH/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29;/h7-8,15-17H,6,9-14,18H2,1-5H3;1H

InChI key: InChIKey=ZRNKXJHEQKMWCH-UHFFFAOYSA-N

SMILES: O(C)C=1C=C2C(=CC1OC)CC(=O)N(CCCN(CCC3=CC(OC)=C(OC)C=C3)C)CC2.Cl

Synonyms:

• 1-(7,8-Dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one-3-yl)-3-[N-methyl-N-[2-(3,4-dimethyoxyphenyl)ethyl]amino]propane hydrochloride
• 2H-3-Benzazepin-2-one, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-, hydrochloride (1:1)
• 2H-3-Benzazepin-2-one, 3-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-, monohydrochloride
• 3-(3-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride
• Ul-Fs-49
• Ulfs 49Cl
• Zatebradine hydrochloride

3-[3-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]METHYLAMINO]PROPYL]-1,3,4,5-TETRAHYDRO-7,8-DIMETHOXY-2H-3-BENZAZEPIN-2-ONE HYDROCHLORIDE

CAS: 91940-87-3

Formula: C₂₆H₃₇ClN₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 493.0354

Ref: IN-DA006JDK

Zatebradine hydrochloride

CAS: 91940-87-3

Zatebradine hydrochloride

Purity: ≥95%

Molecular weight: 493.04g/mol

Ref: 54-BUP13249

Zatebradine hydrochloride

CAS: 91940-87-3

Formula: C₂₆H₃₇ClN₂O₅

Molecular weight: 493.04

Ref: 7W-GP6475

Zatebradine hydrochloride

CAS: 91940-87-3

Zatebradine hydrochloride is a drug which is used to treat bowel disease. It belongs to the class of drugs known as beta-blockers. Zatebradine hydrochloride can be administered intravenously and has been shown to cause a decrease in heart rate and ventricular function in humans. It also has an effect on energy metabolism, cardiac effects, and structural heart disease. This drug has been found to be effective at treating congestive heart failure and atrial fibrillation. Zatebradine hydrochloride also has anti-inflammatory properties that may be due to its ability to inhibit the production of inflammatory cytokines such as IL-1β, IL-6, TNFα, IL-8, and IFNγ.

Formula: C₂₆H₃₆N₂O₅·ClH

Purity: Min. 95%

Molecular weight: 493.04 g/mol

Ref: 3D-RDA94087

Zatebradine hydrochloride

CAS: 91940-87-3

Zatebradine hydrochloride (UL-FS-49CL) inhibits HCN channels (IC50: ~1.9 µM) blocking human HCN1-4 currents effectively.

Formula: C₂₆H₃₇ClN₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 493.04

Ref: TM-T13387L