CAS 92-35-3

Thiochrome

Description:

Thiochrome is a chemical compound characterized by its structure as a thiazole derivative of vitamin B1 (thiamine). It is known for its fluorescent properties, which make it useful in various biochemical applications, particularly in the detection and quantification of thiamine and its derivatives. Thiochrome exhibits a yellow to orange color in solution and can undergo oxidation to form thiochrome sulfonic acid. Its fluorescence is pH-dependent, with optimal emission occurring under specific conditions. The compound is soluble in water and organic solvents, which enhances its utility in laboratory settings. Thiochrome is often utilized in analytical chemistry, especially in assays that measure thiamine levels in biological samples. Additionally, it has been studied for its potential role in neurochemistry, given the importance of thiamine in neurological function. Safety data indicates that, while thiochrome is generally considered to have low toxicity, standard laboratory safety protocols should be followed when handling this compound.

Formula: C₁₂H₁₄N₄OS

InChI: InChI=1S/C12H14N4OS/c1-7-10(3-4-17)18-12-15-11-9(6-16(7)12)5-13-8(2)14-11/h5,17H,3-4,6H2,1-2H3

InChI key: InChIKey=GTQXMAIXVFLYKF-UHFFFAOYSA-N

SMILES: CC=1N2C(=NC=3C(C2)=CN=C(C)N3)SC1CCO

Synonyms:

• 2,7-Dimethyl-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidine-8-ethanol
• 2-(2,7-Dimethyl-5H-pyrimido[4,5-d]thiazolo[3,2-a]pyrimidin-8-yl)ethanol
• 2-(2,7-dimethyl-5H-pyrimido[4,5-d][1,3]thiazolo[3,2-a]pyrimidin-8-yl)ethanol
• 2-(2,7-dimethyl-5H-thiazolo(3,2:1,2)pyrimido(4,5-d)pyrimidin-8-yl)ethanol
• 5H-Pyrimido[4,5-d]thiazolo[3,2-a]pyrimidine-8-ethanol, 2,7-dimethyl-
• NSC 56339
• Thiachromine-8-ethanol, 2,7-dimethyl-
• Thiochrome

5H-Pyrimido[4,5-d]thiazolo[3,2-a]pyrimidine-8-ethanol, 2,7-dimethyl-

CAS: 92-35-3

Formula: C₁₂H₁₄N₄OS

Purity: 99%

Color and Shape: Solid

Molecular weight: 262.3308

Ref: IN-DA00GSEL

Thiochrome

CAS: 92-35-3

Formula: C₁₂H₁₄N₄OS

Molecular weight: 262.33

Ref: 4Z-T-278001

Thiochrome

Controlled Product

CAS: 92-35-3

Applications Thiochrome is a selective M4 muscarinic receptor enhancer of acetylcholine affinity.
References Mohsen, Z., et al.: Food and chemical toxicology, 49 (2011); Lazareno, S., et al.: Molecular pharmacology, 65 (2004);

Formula: C₁₂H₁₄N₄OS

Color and Shape: Neat

Molecular weight: 262.33

Ref: TR-T344875

Thiochrome

CAS: 92-35-3

Thiochrome is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) on the surface of cells. It is used in analytical chemistry for the determination of fatty acids in hydrochloric acid samples. Thiochrome binds to fatty acids and then emits fluorescence when excited by a laser or light-emitting diode. This technique is based on the principle of competitive inhibition. The binding of thiochrome to EGFR inhibits the binding of epidermal growth factor, thereby inhibiting cell proliferation.

Formula: C₁₂H₁₄N₄OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 262.33 g/mol

Ref: 3D-FT66004

Thiochrome

CAS: 92-35-3

Formula: C₁₂H₁₄N₄OS

Molecular weight: 262.33

Ref: ST-EA-CP-T2021

Thiochrome

CAS: 92-35-3

Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.

Formula: C₁₂H₁₄N₄OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 262.33

Ref: TM-T13924