CAS 92-39-7

2-Chlorophenothiazine

Description:

2-Chlorophenothiazine is an organic compound belonging to the phenothiazine class, characterized by its structure that includes a phenothiazine core with a chlorine substituent at the second position of the phenyl ring. It typically appears as a solid with a pale yellow to yellow color and is known for its relatively low solubility in water, but it is soluble in organic solvents such as ethanol and acetone. This compound exhibits properties that make it useful in various applications, including as a pharmaceutical intermediate and in the synthesis of dyes and pigments. 2-Chlorophenothiazine has been studied for its biological activities, including potential antimicrobial and antipsychotic effects, owing to its ability to interact with neurotransmitter systems. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Proper storage in a cool, dry place away from light is recommended to maintain its stability and efficacy.

Formula: C₁₂H₈ClNS

InChI: InChI=1S/C12H8ClNS/c13-8-5-6-12-10(7-8)14-9-3-1-2-4-11(9)15-12/h1-7,14H

InChI key: InChIKey=KFZGLJSYQXZIGP-UHFFFAOYSA-N

SMILES: ClC=1C=C2C(SC=3C(N2)=CC=CC3)=CC1

Synonyms:

• 2-Chloro-10H-phenothiazine
• Phenothiazine, 2-chloro-
• 10H-Phenothiazine, 2-chloro-
• NSC 170953
• 2-Chlorophenothiazine

2-Chlorophenothiazine

CAS: 92-39-7

Formula: C₁₂H₈ClNS

Purity: >98.0%(GC)

Color and Shape: White to Light gray to Green powder to crystal

Molecular weight: 233.71

Ref: 3B-C0248

CHLORPROMAZINE IMPURITY E CRS

CAS: 92-39-7

CHLORPROMAZINE IMPURITY E CRS

Formula: C₁₂H₈ClNS

Molecular weight: 233.7166

Ref: 41-Y0000508

2-Chlorophenothiazine

CAS: 92-39-7

2-Chlorophenothiazine is used as the intermediate of Chlorpromazine hydrochloride.

Formula: C₁₂H₈ClNS

Purity: 98.18%

Color and Shape: Gray Powder

Molecular weight: 233.72

Ref: TM-T0622

2-Chloro-10H-phenothiazine

CAS: 92-39-7

Formula: C₁₂H₈ClNS

Purity: 98%

Color and Shape: Solid

Molecular weight: 233.7166

Ref: IN-DA003H32

Chlorpromazine EP Impurity E

CAS: 92-39-7

Formula: C₁₂H₈ClNS

Color and Shape: Off-White Solid

Molecular weight: 233.71

Ref: 4Z-C-125017

2-Chlorophenothiazine

CAS: 92-39-7

2-Chlorophenothiazine

Purity: 98%

Molecular weight: 233.72g/mol

Ref: 54-OR89806

2-Chlorophenothiazine

CAS: 92-39-7

Formula: C₁₂H₈ClNS

Purity: ≥ 98.0%

Color and Shape: Off-white to yellow or brown powder or crystals

Molecular weight: 233.72

Ref: 7W-GK8483

2-Chlorophenothiazine

CAS: 92-39-7

2-Chlorophenothiazine

Purity: ≥98%

Molecular weight: 233.72g/mol

Ref: 54-BUP16016

2-Chloro-10H-phenothiazine

Controlled Product

CAS: 92-39-7

Formula: C₁₂H₈ClNS

Color and Shape: Neat

Molecular weight: 233.72

Ref: 86-MM0420.04

2-Chloro Phenothiazine

Controlled Product

CAS: 92-39-7

Impurity Chlorpromazine EP Impurity E
Applications Metabolite of Chloropromazine
References Motohashi, N., et al.: Anticancer Res., 17, 4403 (1997), Azuine, M., et al.: Pharmacol. Res., 49, 161 (2004), Touil, F., et al.: J. Pharm. Biomed. Anal., 40, 822 (2006),

Formula: C₁₂H₈ClNS

Color and Shape: Grey

Molecular weight: 233.72

Ref: TR-C374970

2-Chloro-10H-phenothiazine

CAS: 92-39-7

Purity: 95.0%

Color and Shape: Solid, White -to slightly pale yellow green powder

Molecular weight: 233.7100067138672

Ref: 10-F216561

Chlorpromazine EP impurity E

CAS: 92-39-7

Formula: C₁₂H₈ClNS

Molecular weight: 233.72

Ref: ST-EA-CP-C19005

2-Chlorophenothiazine

CAS: 92-39-7

2-Chlorophenothiazine is a chemical substance that can be used as a pharmacological agent. It is classified as an amp-activated protein, which means it binds to the active site of the enzyme phospholipase A2 (PLA2) and thus inhibits its function. 2-Chlorophenothiazine has been shown to inhibit fatty acid biosynthesis by binding to the catalytic site of the enzyme acetyl coenzyme A carboxylase (ACC). This compound also has been shown to have mutagenic properties in bacterial systems, as well as being able to cause damage to red blood cells by inhibiting electron transport in mitochondria. 2-Chlorophenothiazine is also used for treating cancerous cells, such as squamous carcinoma. The activation energy required for 2-chlorophenothiazine's reaction with squamous carcinoma cells is lower than that required for other carcinomas such as leukemia or colon cancer cells.
2-

Formula: C₁₂H₈ClNS

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 233.72 g/mol

Ref: 3D-FC20303