CAS 92-78-4

N-(4-Chlorophenyl)-3-hydroxy-2-naphthalenecarboxamide

Description:

N-(4-Chlorophenyl)-3-hydroxy-2-naphthalenecarboxamide, also known by its CAS number 92-78-4, is a chemical compound characterized by its naphthalene structure substituted with a hydroxyl group and a 4-chlorophenyl group. This compound typically appears as a solid and is known for its potential applications in pharmaceuticals and organic synthesis. The presence of the hydroxyl group contributes to its solubility in polar solvents, while the naphthalene moiety provides aromatic stability and hydrophobic characteristics. The 4-chlorophenyl substituent enhances its biological activity and may influence its interaction with biological targets. This compound may exhibit various biological properties, including antimicrobial or anti-inflammatory activities, making it of interest in medicinal chemistry. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or inhaled. Proper storage and handling protocols are essential to ensure safety in laboratory settings.

Formula: C₁₇H₁₂ClNO₂

InChI: InChI=1S/C17H12ClNO2/c18-13-5-7-14(8-6-13)19-17(21)15-9-11-3-1-2-4-12(11)10-16(15)20/h1-10,20H,(H,19,21)

InChI key: InChIKey=OHAXNCGNVGGWSO-UHFFFAOYSA-N

SMILES: C(NC1=CC=C(Cl)C=C1)(=O)C2=CC3=C(C=C2O)C=CC=C3

Synonyms:

• 2-Hydroxy-3-Naphthoyl-p-Chloraniline
• 2-Naphthalenecarboxamide, N-(4-chlorophenyl)-3-hydroxy-
• 2-Naphthanilide, 4′-chloro-3-hydroxy-
• 3-Hydroxy-4′-chloro-2-naphthanilide
• 4′-Chloro-3-hydroxy-2-naphthanilide
• Acna Naphthol PC
• Amanil Naphthol AS-E
• Amarthol AS-E
• Anarthol AS-E
• Azoic Coupling Component 10
• Cibanaphthol RC
• Conazoic AO
• Daito Grounder E
• Dycosthol AS-E
• Hiltonaphthol AS-E
• Kako Grounder E
• Kiwa Grounder E
• N-(4-Chlorophenyl)-3-hydroxy-2-naphthalenecarboxamide
• N-(4-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide
• NSC 50684
• Naftol AS-E
• Naphtanilide E
• Naphtazol E
• Naphthol ACNA PC
• Naphtoelan E
• Naphtol AS-E Supra
• Napthol ASE
• Red RC Base
• Sanatol E
• Tulathol AS-E
• C.I. 37510
• C.I. Azoic Coupling Component 10

4'-Chloro-3-hydroxy-2-naphthanilide

CAS: 92-78-4

Formula: C₁₇H₁₂ClNO₂

Purity: >97.0%(N)

Color and Shape: White to Light yellow to Dark green powder to crystal

Molecular weight: 297.74

Ref: 3B-C2103

N-(4-Chlorophenyl)-3-hydroxy-2-naphthalenecarboxamide

CAS: 92-78-4

Formula: C₁₇H₁₂ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 297.7357

Ref: IN-DA0033ZI

Naphthol AS-E

CAS: 92-78-4

Naphthol AS-E

Purity: ≥98%

Molecular weight: 297.74g/mol

Ref: 54-BUP16841

Naphthol AS-E

CAS: 92-78-4

Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor.

Formula: C₁₇H₁₂ClNO₂

Purity: 99.33%

Color and Shape: Grey Solid Powder

Molecular weight: 297.74

Ref: TM-T7856

N-(4-Chlorophenyl)-3-hydroxy-2-naphthamide

CAS: 92-78-4

Purity: 95.0%

Molecular weight: 297.739990234375

Ref: 10-F498971

C.I.Azoic Coupling Component 10

CAS: 92-78-4

C.I.Azoic Coupling Component 10 is a molecule that has anticancer activity in the PC3 cancer cell line and the MDA-MB-231 breast cancer cell line. It is an inhibitor of the transcription factor, response element binding protein (REB). The molecule binds to DNA in a manner similar to that of platinum drugs and inhibits the synthesis of RNA by inhibiting RNA polymerase II. C.I.Azoic Coupling Component 10 also exhibits cytotoxic effects on leukemia cells, such as mcf-7 cells, which are resistant to chemotherapeutic agents.
The molecule is activated by hydroxyl groups and carbonyl groups in cancer tissues, which may be due to its ability to bind with factor receptors on tumor cells and inhibit their growth.

Formula: C₁₇H₁₂ClNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 297.74 g/mol

Ref: 3D-FA41321