CAS 920-36-5: Isobutyllithium

Description: Isobutyllithium is an organolithium compound with the chemical formula C4H7Li. It is characterized by its highly reactive nature, primarily due to the presence of the lithium atom bonded to a carbon atom, which makes it a strong nucleophile and a powerful base. Isobutyllithium is typically a colorless to yellow liquid at room temperature and is often used in organic synthesis, particularly in the formation of carbon-carbon bonds through nucleophilic addition reactions. It is soluble in non-polar solvents such as hexane and diethyl ether but reacts vigorously with water and alcohols, releasing flammable gases and potentially causing hazardous situations. Due to its reactivity, isobutyllithium must be handled under inert atmospheres, such as nitrogen or argon, and stored in tightly sealed containers to prevent moisture exposure. Safety precautions are essential when working with this compound, as it can cause severe chemical burns and is a fire hazard. Its applications extend to the synthesis of various organic compounds, including pharmaceuticals and polymers.

Formula: C₄H₉Li

InChI: InChI=1S/C4H9.Li/c1-4(2)3;/h4H,1H2,2-3H3;

InChI key: InChIKey=YZLMQRULZXAMEC-UHFFFAOYSA-N

SMILES: [Li]CC(C)C

Synonyms:

• Lithium, (2-methylpropyl)-
• Isobutyllithium
• Lithium, isobutyl-

Isobutyllithium

CAS: 920-36-5

• Formula: C₄H₉Li
• Molecular weight: 64.0553

Isobutyllithium, 1.6M solution in heptane, AcroSeal™

CAS: 64742-49-0 920-36-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Color and Shape: Solution, Colorless to yellow, May develop some turbidity or precipitate