CAS 920509-32-6

1,2,4-Triazine-6-carbonitrile,2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-

Description:

1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo- is a complex organic compound characterized by its multi-ring structure and various functional groups. This substance features a triazine ring, which is a six-membered heterocyclic compound containing three nitrogen atoms, contributing to its potential reactivity and biological activity. The presence of a carbonitrile group indicates a strong electron-withdrawing character, which can influence the compound's chemical behavior. Additionally, the dichloro substituents and the pyridazinyl moiety suggest potential applications in pharmaceuticals or agrochemicals, as such structures are often associated with bioactivity. The compound's tetrahydro and dioxo functionalities may also enhance its solubility and stability in various solvents. Overall, this compound's unique structural features make it a subject of interest for further research in medicinal chemistry and material science.

Formula: C₁₇H₁₂Cl₂N₆O₄

1,2,4-Triazine-6-carbonitrile,2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro-3,5-dioxo-

CAS: 920509-32-6

Formula: C₁₇H₁₂Cl₂N₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 435.2210

Ref: IN-DA01DOV2

Resmetirom

CAS: 920509-32-6

Resmetirom

Purity: ≥98%

Molecular weight: 435.22g/mol

Ref: 54-BUP15063

2-(3,5-Dichloro-4-((5-Isopropyl-6-Oxo-1,6-Dihydropyridazin-3-Yl)Oxy)Phenyl)-3,5-Dioxo-2,3,4,5-Tetrahydro-1,2,4-Triazine-6-Carbonitrile

CAS: 920509-32-6

2-(3,5-Dichloro-4-((5-Isopropyl-6-Oxo-1,6-Dihydropyridazin-3-Yl)Oxy)Phenyl)-3,5-Dioxo-2,3,4,5-Tetrahydro-1,2,4-Triazine-6-Carbonitrile

Purity: 98%

Molecular weight: 435.22g/mol

Ref: 54-OR1023362

Resmetirom

CAS: 920509-32-6

Formula: C₁₇H₁₂Cl₂N₆O₄

Molecular weight: 435.22

Ref: 4Z-R-165001

Resmetirom-13C3-15N

CAS: 920509-32-6

Formula: C₁₄₁₃C₃H₁₂Cl₂N₅₁₅NO₄

Molecular weight: 439.19

Ref: 4Z-R-165002

Resmetirom

CAS: 920509-32-6

Resmetirom (MGL-3196) is a THR-β agonist (EC50=0.21 μM), with high selectivity and oral activity. High-Quality, Low-Cost!

Formula: C₁₇H₁₂Cl₂N₆O₄

Purity: 99.05% - >99.99%

Color and Shape: Solid

Molecular weight: 435.22

Ref: TM-T3595

Resmetirom

CAS: 920509-32-6

Resmetirom, also known as MGL-3196, is a promising drug for the treatment of hyperlipidemia and nonalcoholic steatohepatitis (NASH)(now known as metabolic dysfunction-associated steatohepatitis (MASH). It is an orally active, liver-directed, selective thyroid hormone receptor-beta agonist. Resmetirom works by targeting the thyroid hormone receptor-beta to regulate hepatic triglyceride and cholesterol metabolism, thereby reducing hepatic fat content. In clinical trials, resmetirom has shown significant reductions in liver fat content in patients with NASH without major side effects. Additionally, resmetirom has been found to improve atherogenic dyslipidemia associated with NASH by positively impacting triglyceride and LDL cholesterol levels.

Formula: C₁₇H₁₂Cl₂N₆O₄

Purity: (%) Min. 99%

Molecular weight: 435.22 g/mol

Ref: 3D-VLB50932