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CAS 920519-31-9

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FMOC-TYR(TBU)-THR(PSI-ME,MEPRO)-OH

Description:
FMOC-TYR(TBU)-THR(PSI-ME,MEPRO)-OH is a protected amino acid derivative commonly used in peptide synthesis. The FMOC (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The presence of the TBU (tert-butyl) group indicates that the side chain of tyrosine is protected, which is crucial for maintaining the integrity of the amino acid during synthesis. The THR (threonine) component is also modified, with PSI-ME (a specific modification) and MEPRO (likely a proline derivative) indicating further structural complexity. This compound is typically utilized in solid-phase peptide synthesis, where the protection and deprotection of functional groups are essential for the successful assembly of peptides. Its unique structure allows for the incorporation of specific functionalities that can enhance the properties of the resulting peptides, such as stability and bioactivity. Overall, FMOC-TYR(TBU)-THR(PSI-ME,MEPRO)-OH is a valuable building block in the field of medicinal chemistry and peptide research.
Formula:C35H40N2O7
InChI:InChI=1S/C35H40N2O7/c1-21-30(32(39)40)37(35(5,6)43-21)31(38)29(19-22-15-17-23(18-16-22)44-34(2,3)4)36-33(41)42-20-28-26-13-9-7-11-24(26)25-12-8-10-14-27(25)28/h7-18,21,28-30H,19-20H2,1-6H3,(H,36,41)(H,39,40)/t21-,29+,30+/m1/s1
InChI key:JYSMURJYNLWZNY-RIGQTMPJSA-N
SMILES:C[C@@H]1[C@H](N(C(O1)(C)C)C(=O)[C@H](CC2=CC=C(C=C2)OC(C)(C)C)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)C(=O)O
Synonyms:
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Tyr(tBu)-ThrPsi(Me, Me)Pro-OH
  • Fmoc-L-Tyr(tBu)-L-Thr[PSI(Me,Me)Pro]-OH
  • Fmoc-Tyr(tBu)-Thr[Psi(Me,Me)Pro]-OH≥ 99% (HPLC)
  • (4S)-3-[(2S)-3-[4-(1,1-Dimethylethoxy)phenyl]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2,5-trimethyl-4-oxazolidinecarboxylic acid
  • (4S,5R)-3-[(2S)-3-[4-(tert-butoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-2,2,5-trimethyl-1,3-oxazolidine-4-carboxylic acid
  • FMOC-TYR(TBU)-THR(ΨME,ME PRO)-OH_920519-31-9
  • Fmoc-Tyr(tBu)-Thr(ΨMe,Mepro)-OH
  • 4-Oxazolidinecarboxylic acid, 3-[(2S)-3-[4-(1,1-dimethylethoxy)phenyl]-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2,5-trimethyl-, (4S)-
  • FMOC-TYR(TBU)-THR(PSI-ME,MEPRO)-OH
  • (4S,5R)-3-[Nα-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-tyrosinyl]-2,2,5-trimethyloxazolidine-4-carboxylic acid
Found 5 products.