CAS 92083-03-9

4a,5-Dihydro Simvastatin

Controlled Product

CAS: 92083-03-9

Impurity Simvastatin Impurity K
Applications 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),

Formula: C₂₅H₄₀O₅

Color and Shape: Neat

Molecular weight: 420.58

Ref: TR-D450010