CAS 92090-94-3

(2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid

Description:

The chemical substance with the name "(2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid" and CAS number "92090-94-3" is a complex organic molecule characterized by multiple stereocenters and a long carbon chain. It features various functional groups, including hydroxyl (-OH) and keto (C=O) groups, which contribute to its reactivity and potential biological activity. The presence of multiple double bonds in the carbon chain indicates that it is an unsaturated fatty acid derivative, which may play a role in biological processes or serve as a precursor for other bioactive compounds. The stereochemistry of the molecule suggests specific spatial arrangements that can influence its interaction with biological targets, making it of interest in fields such as biochemistry and pharmacology. Overall, this compound exemplifies the complexity and diversity of organic molecules found in nature, particularly in relation to their structural and functional properties.

Formula: C₃₃H₄₈O₇

InChI: InChI=1S/C33H48O7/c1-8-27(13-14-29-24(5)12-15-31(37)40-29)17-21(2)10-9-11-22(3)18-28(20-34)33(39)26(7)32(38)25(6)16-23(4)19-30(35)36/h9,11-15,17-19,21,24-26,28-29,32,34,38H,8,10,16,20H2,1-7H3,(H,35,36)/b11-9+,14-13+,22-18+,23-19+,27-17-/t21-,24+,25+,26+,28+,29+,32-/m1/s1

InChI key: InChIKey=KZMHNEBMQDBQND-LBNZKSCFSA-N

SMILES: C(=C/C(=C\[C@@H](C/C=C/C(=C/[C@H](C([C@H]([C@@H]([C@H](C/C(=C/C(O)=O)/C)C)O)C)=O)CO)/C)C)/CC)\[C@H]1[C@@H](C)C=CC(=O)O1

Synonyms:

• (2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid
• Kazusamycin A
• Antibiotic 81-484
• 2,10,12,16,18-Nonadecapentaenoic acid, 19-[(2S,3S)-3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-8-oxo-, (2E,5S,6R,7S,9S,10E,12E,15R,16Z,18E)-
• PD 114721

Kazusamycin A

CAS: 92090-94-3

Kazusamycin A is a new antitumor antibiotic.

Formula: C₃₃H₄₈O₇

Color and Shape: Solid

Molecular weight: 556.74

Ref: TM-T24253

Kazusamycin A

CAS: 92090-94-3

Molecular weight: 556.7

Ref: 7W-GA4695

Kazusamycin A

Controlled Product

CAS: 92090-94-3

Formula: C₃₃H₄₈O₇

Color and Shape: Neat

Molecular weight: 556.73

Ref: TR-K445003

Kazusamycin A

CAS: 92090-94-3

Kazusamycin A is a β-amino acid that has potent antitumor activity. It inhibits the growth of subcutaneous tumors in mice, and has been shown to inhibit protein synthesis. Kazusamycin A also has potent inhibitory activity against fatty acid synthase, which is an enzyme that catalyzes the synthesis of fatty acids from acetyl-CoA. This inhibition may be responsible for its potent anti-tumor effects, as well as its ability to prevent tumor metastasis and cancer progression. Kazusamycin A also has been shown to have immunosuppressive effects and could be used for the treatment of autoimmune diseases such as rheumatoid arthritis or lupus erythematosus.

Formula: C₃₃H₄₈O₇

Purity: Min. 95%

Molecular weight: 556.7 g/mol

Ref: 3D-SDA09094